Table. 12—

ESC/ERS guidelines: recommendations for pulmonary hypertension (PH) due to left heart disease

StatementClass#Level
The optimal treatment of the underlying left heart disease is recommended in patients with PH due to left heart diseaseIC
Patients with “out of proportion” PH due to left heart disease (table 3) should be enrolled in RCTs targeting PH specific drugsIIaC
Increased left-sided filling pressures may be estimated by Doppler echocardiographyIIbC
Invasive measurements of Ppcw or LV end-diastolic pressure may be required to confirm the diagnosis of PH due to left heart diseaseIIbC
RHC may be considered in patients with echocardiographic signs suggesting severe PH in patients with left heart diseaseIIbC
The use of PAH specific drug therapy is not recommended in patients with PH due to left heart diseaseIIIC
  • RCT: randomised controlled trial; Ppcw: pulmonary capillary wedge pressure; LV: left ventricular; RHC: right heart catheterisation; PAH: pulmonary arterial hypertension. #: class of recommendation; : level of evidence. Reproduced from 1 with permission from the publisher.