Table 1—

Current biomarkers, biological interest and potential use in chronic obstructive pulmonary disease(COPD)

BiomarkersBiological interestPotential use in COPD
CRPMarker of systemic inflammationIdentify aetiological origin of exacerbation
Monitor short- and long-term prognosis
PCTMarker of systemic bacterial infectionIdentify bacterial exacerbations
Assess treatment effect
NeopterinMarker of infection by pathogens activating cellular immunityIdentify aetiological origin of exacerbation
Assess treatment effect
CopeptinMarker of homeostasis deregulationMonitor short- and long-term prognosis
Pro-ANPMarker of cardiovascular/renal dysfunctionMonitor short- and long-term prognosis
Pro-ADMMarker of cardiovascular/renal dysfunctionMonitor short- and long-term prognosis
  • CRP: C-reactive protein; PCT: procalcitonin; pro-ANP: pro-atrial natriuretic peptide; pro-ADM: pro-adrenomedullin.