Within group change after PR (95% CI) | Between group mean difference | ||
Creatine | Placebo | ||
Subjects n | 38 | 42 | |
Weight kg | 0.8 (0.2–1.3)** | 0.2 (−0.4–0.8) | 0.5 (−0.3–1.3) |
FFM | 0.9 (0.1–1.7)* | 0.8 (−0.05–1.6) | 0.1 (−1.0–1.3) |
ISWT m | 84.0 (58.0–109.9)** | 83.8 (65.0, 102.6)** | 0.1 (−30.9–31.2) |
ESWT s | 377.4 (248.6–506.3)** | 487.4 (367.2–607.6)** | −110.0 (−283.3–63.3) |
Isokinetic quadriceps strength N·m | 19.2 (14.0–24.3)** | 19.5 (14.2–24.7)** | −0.3 (−7.6–7.0) |
Isometric quadriceps strength N·m | 19.6 (16.0–23.3)** | 23.1 (17.8–28.4)** | −3.5 (−10.0–3.0) |
PR: pulmonary rehabilitation; CI: confidence interval; FFM, fat-free mass; ISWT: incremental shuttle walking test; ESWT: endurance shuttle walking test. *: p<0.05; **: p<0.01.