Table 1—
Within group change after PR (95% CI)Between group mean difference
CreatinePlacebo
Subjects n 3842
Weight kg 0.8 (0.2–1.3)**0.2 (−0.4–0.8)0.5 (−0.3–1.3)
FFM 0.9 (0.1–1.7)*0.8 (−0.05–1.6)0.1 (−1.0–1.3)
ISWT m 84.0 (58.0–109.9)**83.8 (65.0, 102.6)**0.1 (−30.9–31.2)
ESWT s 377.4 (248.6–506.3)**487.4 (367.2–607.6)**−110.0 (−283.3–63.3)
Isokinetic quadriceps strength N·m 19.2 (14.0–24.3)**19.5 (14.2–24.7)**−0.3 (−7.6–7.0)
Isometric quadriceps strength N·m 19.6 (16.0–23.3)**23.1 (17.8–28.4)**−3.5 (−10.0–3.0)
  • PR: pulmonary rehabilitation; CI: confidence interval; FFM, fat-free mass; ISWT: incremental shuttle walking test; ESWT: endurance shuttle walking test. *: p<0.05; **: p<0.01.