Table. 1—

Haemodynamic parameters on presentation and following treatment with bosentan plus high doses of furosemide

Presentation#Bosentan plus furosemide
Heart rate beats·min−1120110
Right atrial pressure mmHg113
Pulmonary artery pressure s/d/m mmHg98/50/7085/48/63
Pulmonary wedge pressure mmHg108
Trans-pulmonary gradient mmHg6055
Blood pressure s/d/m mmHg102/76/9094/73/79
Cardiac output L·min12.54.0
Cardiac index L·min−1·m−21.42.4
PVR mmHg·L−1·min−12413.8
SVR mmHg·L−1·min−131.619.0
Sa,O2 %8895
Sv,O2 %39.160
  • s: systolic; d: diastolic; m: mean; PVR: pulmonary vascular resistance; SVR: systemic vascular resistance; Sa,O2: arterial oxygen saturation; Sv,O2: mixed venous oxygen saturation. #: oxygen, 6 L·min−1; : breathing room air.