RT Journal Article
SR Electronic
T1 Quality of life in patients with chronic respiratory failure on home mechanical ventilation
JF European Respiratory Review
JO EUROPEAN RESPIRATORY REVIEW
FD European Respiratory Society
SP 220237
DO 10.1183/16000617.0237-2022
VO 32
IS 168
A1 D'Cruz, Rebecca F.
A1 Kaltsakas, Georgios
A1 Suh, Eui-Sik
A1 Hart, Nicholas
YR 2023
UL https://publications.ersnet.org//content/32/168/220237.abstract
AB Home mechanical ventilation (HMV) is a treatment for chronic respiratory failure that has shown clinical and cost effectiveness in patients with underlying COPD, obesity-related respiratory failure and neuromuscular disease (NMD). By treating chronic respiratory failure with adequate adherence to HMV, improvement in patient-reported outcomes including health-related quality of life (HRQoL) have been evaluated using general and disease-specific quantitative, semi-qualitative and qualitative methods. However, the treatment response in terms of trajectory of change in HRQoL is not uniform across the restrictive and obstructive disease groups. In this review, the effect of HMV on HRQoL across the domains of symptom perception, physical wellbeing, mental wellbeing, anxiety, depression, self-efficacy and sleep quality in stable and post-acute COPD, rapidly progressive NMD (such as amyotrophic lateral sclerosis), inherited NMD (including Duchenne muscular dystrophy) and obesity-related respiratory failure will be discussed.Home ventilation can improve clinical outcomes for patients with COPD, obesity-related respiratory failure and neuromuscular disease. A range of modifiable and nonmodifiable factors influence its impact upon patients’ health-related quality of life. https://bit.ly/3Xsak4I