TY - JOUR T1 - Diagnostic workup of childhood interstitial lung disease JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW DO - 10.1183/16000617.0188-2022 VL - 32 IS - 167 SP - 220188 AU - Nadia Nathan AU - Matthias Griese AU - Katarzyna Michel AU - Julia Carlens AU - Carlee Gilbert AU - Nagehan Emiralioglu AU - Alba Torrent-Vernetta AU - Honorata Marczak AU - Brigitte Willemse AU - Céline Delestrain AU - Ralph Epaud A2 - , Y1 - 2023/03/31 UR - http://err.ersjournals.com/content/32/167/220188.abstract N2 - Childhood interstitial lung diseases (chILDs) are rare and heterogeneous diseases with significant morbidity and mortality. An accurate and quick aetiological diagnosis may contribute to better management and personalised treatment. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review summarises the roles of the general paediatrician, paediatric pulmonologists and expert centres in the complex diagnostic workup. Each patient's aetiological chILD diagnosis must be reached without prolonged delays in a stepwise approach from medical history, signs, symptoms, clinical tests and imaging, to advanced genetic analysis and specialised procedures including bronchoalveolar lavage and biopsy, if necessary. Finally, as medical progress is fast, the need to revisit a diagnosis of “undefined chILD” is stressed.Childhood interstitial lung diseases are rare and severe diseases. A stepwise approach to an aetiological diagnosis includes specific investigations performed in expert centres. The term “undefined chILD” must be regularly reassessed. https://bit.ly/3YIWKvn ER -