PT  - JOURNAL ARTICLE
AU  - Daphne W. Dumoulin
AU  - Paolo Bironzo
AU  - Francesco Passiglia
AU  - Giorgio V. Scagliotti
AU  - Joachim G.J.V. Aerts
ED  - ,
TI  - Rare thoracic cancers: a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours
AID  - 10.1183/16000617.0174-2022
DP  - 2023 Mar 31
TA  - European Respiratory Review
PG  - 220174
VI  - 32
IP  - 167
4099  - http://err.ersjournals.com/content/32/167/220174.short
4100  - http://err.ersjournals.com/content/32/167/220174.full
SO  - EUROPEAN RESPIRATORY REVIEW2023 Mar 31; 32
AB  - Despite the progress in outcomes seen with immunotherapy in various malignancies, including nonsmall cell lung cancer, the benefits are less in small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours. New effective treatment options are needed, guided via more in-depth insights into the pathophysiology of these rare malignancies. This review comprehensively presents an overview of the clinical presentation, diagnostic tools, staging systems, pathophysiology and treatment options for these rare thoracic cancers. In addition, opportunities for further improvement of therapies are discussed.SCLC, mesothelioma and thymoma are rare thoracic cancers. Diagnosis and treatment options should therefore be discussed in a multidisciplinary discussion. Although progress has been made with the entrance of ICI, novel strategies are being studied. https://bit.ly/3TTUgY9