PT - JOURNAL ARTICLE AU - Mona Bafadhel AU - Rosa Faner AU - Camille Taillé AU - Richard E.K. Russell AU - Tobias Welte AU - Peter J. Barnes AU - Alvar Agustí TI - Inhaled corticosteroids for the treatment of COVID-19 AID - 10.1183/16000617.0099-2022 DP - 2022 Dec 31 TA - European Respiratory Review PG - 220099 VI - 31 IP - 166 4099 - http://err.ersjournals.com/content/31/166/220099.short 4100 - http://err.ersjournals.com/content/31/166/220099.full SO - EUROPEAN RESPIRATORY REVIEW2022 Dec 31; 31 AB - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused severe illness and mortality for millions worldwide. Despite the development, approval and rollout of vaccination programmes globally to prevent infection by SARS-CoV-2 and the development of coronavirus disease 2019 (COVID-19), treatments are still urgently needed to improve outcomes. Early in the pandemic it was observed that patients with pre-existing asthma or COPD were underrepresented among those with COVID-19. Evidence from clinical studies indicates that the inhaled corticosteroids (ICS) routinely taken for asthma and COPD could have had a protective role in preventing severe COVID-19 and, therefore, may be a promising treatment for COVID-19. This review summarises the evidence supporting the beneficial effects of ICS on outcomes in patients with COVID-19 and explores the potential protective mechanisms.Treatments are urgently needed to improve outcomes for patients with coronavirus disease 2019 (COVID-19) infection. This review summarises the evidence for the potential protective role of inhaled corticosteroids in preventing severe COVID-19 https://bit.ly/3yCAvfn