PT  - JOURNAL ARTICLE
AU  - Kinaupenne, Manon
AU  - De Craemer, Marieke
AU  - Schaballie, Heidi
AU  - Vandekerckhove, Kristof
AU  - Van Biervliet, Stephanie
AU  - Demeyer, Heleen
TI  - Physical activity and its correlates in people with cystic fibrosis: a systematic review
AID  - 10.1183/16000617.0010-2022
DP  - 2022 Sep 30
TA  - European Respiratory Review
PG  - 220010
VI  - 31
IP  - 165
4099  - http://err.ersjournals.com/content/31/165/220010.short
4100  - http://err.ersjournals.com/content/31/165/220010.full
SO  - EUROPEAN RESPIRATORY REVIEW2022 Sep 30; 31
AB  - Cystic fibrosis (CF) is a life-shortening genetic disease, affecting multiple life domains including physical activity (PA). Although higher PA levels are associated with multiple health benefits, little insight exists on the PA level of people with CF (PwCF) compared to healthy peers. Evidence on the influencing factors (i.e. correlates) of PA in this clinical population is scarce, but essential to fully understand their PA behaviour. Therefore, the present review aims to provide an overview of the PA level of PwCF compared to healthy peers, and the correlates of PA in PwCF. A systematic search of three databases resulted in 46 included studies. Analysis of 16 studies showed that the CF population is equally active compared to healthy peers, but there is a trend towards less high-intensity PA in youths with CF. Furthermore, PA is positively associated with quality of life, lung function, (maximal) exercise capacity, bone mineral density and quadriceps force. Also, PA was lower on weekdays compared to weekend days and lower when experiencing pulmonary exacerbations. More high-quality research is required in PwCF, particularly longitudinal studies that further explore the correlates of PA, with PA investigated as a primary outcome and measured objectively.PwCF are as active as their healthy peers but a trend for less high-intensity PA is seen in youths with CF. This systematic review stresses the need for high-quality longitudinal studies to further unravel the PA levels of PwCF and its influencing factors. https://bit.ly/3npYkRn