RT Journal Article SR Electronic T1 Interstitial lung disease in infancy and early childhood: a clinicopathological primer JF European Respiratory Review JO EUROPEAN RESPIRATORY REVIEW FD European Respiratory Society SP 210251 DO 10.1183/16000617.0251-2021 VO 31 IS 163 A1 Laenger, Florian Peter A1 Schwerk, Nicolaus A1 Dingemann, Jens A1 Welte, Tobias A1 Auber, Bernd A1 Verleden, Stijn A1 Ackermann, Maximilian A1 Mentzer, Steven J. A1 Griese, Matthias A1 Jonigk, Danny YR 2022 UL https://publications.ersnet.org//content/31/163/210251.abstract AB Children's interstitial lung disease (chILD) encompasses a wide and heterogeneous spectrum of diseases substantially different from that of adults. Established classification systems divide chILD into conditions more prevalent in infancy and other conditions occurring at any age. This categorisation is based on a multidisciplinary approach including clinical, radiological, genetic and histological findings. The diagnostic evaluation may include lung biopsies if other diagnostic approaches failed to identify a precise chILD entity, or if severe or refractory respiratory distress of unknown cause is present. As the majority of children will be evaluated and diagnosed outside of specialist centres, this review summarises relevant clinical, genetic and histological findings of chILD to provide assistance in clinical assessment and rational diagnostics.ILD of childhood is comparable by name only to lung disease in adults. A dedicated interdisciplinary team is required to achieve the best possible outcome. This review summarises the current clinicopathological criteria and associated genetic alterations. https://bit.ly/3mpxI3b