RT Journal Article SR Electronic T1 Post-acute COVID-19 syndrome JF European Respiratory Review JO EUROPEAN RESPIRATORY REVIEW FD European Respiratory Society SP 210185 DO 10.1183/16000617.0185-2021 VO 31 IS 163 A1 David Montani A1 Laurent Savale A1 Nicolas Noel A1 Olivier Meyrignac A1 Romain Colle A1 Matthieu Gasnier A1 Emmanuelle Corruble A1 Antoine Beurnier A1 Etienne-Marie Jutant A1 Tài Pham A1 Anne-Lise Lecoq A1 Jean-François Papon A1 Samy Figueiredo A1 Anatole Harrois A1 Marc Humbert A1 Xavier Monnet A1 , YR 2022 UL http://err.ersjournals.com/content/31/163/210185.abstract AB Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic that has resulted in millions of deaths and a major strain on health systems worldwide. Medical treatments for COVID-19 (anticoagulants, corticosteroids, anti-inflammatory drugs, oxygenation therapy and ventilation) and vaccination have improved patient outcomes. The majority of patients will recover spontaneously or after acute-phase management, but clinicians are now faced with long-term complications of COVID-19 including a large variety of symptoms, defined as “post-acute COVID-19 syndrome”. Most studies have focused on patients hospitalised for severe COVID-19, but acute COVID-19 syndrome is not restricted to these patients and exists in outpatients. Given the diversity of symptoms and the high prevalence of persistent symptoms, the management of these patients requires a multidisciplinary team approach, which will result in the consumption of large amounts of health resources in the coming months. In this review, we discuss the presentation, prevalence, pathophysiology and evolution of respiratory complications and other organ-related injuries associated with post-acute COVID-19 syndrome.Given the millions of patients infected with SARS-CoV-2 worldwide and the need for multidisciplinary management of the chronic complications, post-acute COVID-19 syndrome will be a major issue for various healthcare providers in the coming months. https://bit.ly/3lBJuXu