PT  - JOURNAL ARTICLE
AU  - David A. Kaminsky
AU  - Shannon J. Simpson
AU  - Kenneth I. Berger
AU  - Peter Calverley
AU  - Pedro L. de Melo
AU  - Ronald Dandurand
AU  - Raffaele L. Dellacà
AU  - Claude S. Farah
AU  - Ramon Farré
AU  - Graham L. Hall
AU  - Iulia Ioan
AU  - Charles G. Irvin
AU  - David W. Kaczka
AU  - Gregory G. King
AU  - Hajime Kurosawa
AU  - Enrico Lombardi
AU  - Geoffrey N. Maksym
AU  - François Marchal
AU  - Ellie Oostveen
AU  - Beno W. Oppenheimer
AU  - Paul D. Robinson
AU  - Maarten van den Berge
AU  - Cindy Thamrin
TI  - Clinical significance and applications of oscillometry
AID  - 10.1183/16000617.0208-2021
DP  - 2022 Mar 31
TA  - European Respiratory Review
PG  - 210208
VI  - 31
IP  - 163
4099  - http://err.ersjournals.com/content/31/163/210208.short
4100  - http://err.ersjournals.com/content/31/163/210208.full
SO  - EUROPEAN RESPIRATORY REVIEW2022 Mar 31; 31
AB  - Recently, “Technical standards for respiratory oscillometry” was published, which reviewed the physiological basis of oscillometric measures and detailed the technical factors related to equipment and test performance, quality assurance and reporting of results. Here we present a review of the clinical significance and applications of oscillometry. We briefly review the physiological principles of oscillometry and the basics of oscillometry interpretation, and then describe what is currently known about oscillometry in its role as a sensitive measure of airway resistance, bronchodilator responsiveness and bronchial challenge testing, and response to medical therapy, particularly in asthma and COPD. The technique may have unique advantages in situations where spirometry and other lung function tests are not suitable, such as in infants, neuromuscular disease, sleep apnoea and critical care. Other potential applications include detection of bronchiolitis obliterans, vocal cord dysfunction and the effects of environmental exposures. However, despite great promise as a useful clinical tool, we identify a number of areas in which more evidence of clinical utility is needed before oscillometry becomes routinely used for diagnosing or monitoring respiratory disease.This paper provides a current review of the interpretation, clinical significance and application of oscillometry in respiratory medicine, with special emphasis on limitations of evidence and suggestions for future research. https://bit.ly/3GQPViA