RT Journal Article
SR Electronic
T1 Sex, gender and the pulmonary physiology of exercise
JF European Respiratory Review
JO EUROPEAN RESPIRATORY REVIEW
FD European Respiratory Society
SP 210074
DO 10.1183/16000617.0074-2021
VO 31
IS 163
A1 Paolo B. Dominelli
A1 Yannick Molgat-Seon
YR 2022
UL http://err.ersjournals.com/content/31/163/210074.abstract
AB In this review, we detail how the pulmonary system's response to exercise is impacted by both sex and gender in healthy humans across the lifespan. First, the rationale for why sex and gender differences should be considered is explored, and then anatomical differences are highlighted, namely that females typically have smaller lungs and airways than males. Thereafter, we describe how these anatomical differences can impact functional aspects such as respiratory muscle energetics and activation, mechanical ventilatory constraints, diaphragm fatigue, and pulmonary gas exchange in healthy adults and children. Finally, we detail how gender can impact the pulmonary response to exercise.Biological sex can influence the pulmonary response to exercise in healthy individuals across the lifespan https://bit.ly/3ejMDrv