TY - JOUR T1 - Mediastinal tumours and pseudo-tumours: a comprehensive review with emphasis on multidisciplinary approach JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW DO - 10.1183/16000617.0309-2020 VL - 30 IS - 162 SP - 200309 AU - Maria-Rosa Ghigna AU - Vincent Thomas de Montpreville Y1 - 2021/12/31 UR - http://err.ersjournals.com/content/30/162/200309.abstract N2 - The diagnosis of a mediastinal mass may be challenging for clinicians, since lesions arising within the mediastinum include a variety of disease entities, frequently requiring a multidisciplinary approach. Age and sex represent important information, which need to be integrated with imaging and laboratory findings. In addition, the location of the mediastinal lesion is fundamental; indeed, we propose to illustrate mediastinal diseases based on the compartment of origin. We consider that this structured approach may serve as hint to the diagnostic modalities and management of mediastinal diseases. In this review, we present primary mediastinal tumours in the evolving context of new diagnostic and therapeutic tools, with recently described entities, based on our own experience with >900 cases encountered in the past 10 years.Given the mediastinal anatomical heterogeneity, the correct positioning of mediastinal lesions becomes primal, in order to first establish a clinical suspicion and then to assist in planning biopsy and surgical procedure https://bit.ly/3p0gsk3 ER -