PT - JOURNAL ARTICLE AU - Eihab O. Bedawi AU - Julien Guinde AU - Najiib M. Rahman AU - Philippe Astoul TI - Advances in pleural infection and malignancy AID - 10.1183/16000617.0002-2020 DP - 2021 Mar 31 TA - European Respiratory Review PG - 200002 VI - 30 IP - 159 4099 - http://err.ersjournals.com/content/30/159/200002.short 4100 - http://err.ersjournals.com/content/30/159/200002.full SO - EUROPEAN RESPIRATORY REVIEW2021 Mar 31; 30 AB - Pleural infection and malignancy are among the most common causes of pleural disease and form the mainstay of pleural practice. There has been significant research and increase in scientific understanding in these areas in the past decade. With regard to pleural infection, the rising incidence remains worrying. An increased awareness allowing earlier diagnosis, earlier escalation of therapy and the use of validated risk stratification measures may improve outcomes. In pleural malignancy, research has enabled clinicians to streamline patient pathways with focus on reducing time to diagnosis, definitive management of malignant pleural effusion and achieving these with the minimum number of pleural interventions. Trials comparing treatment modalities of malignant pleural effusion continue to highlight the importance of patient choice in clinical decision-making. This article aims to summarise some of the most recent literature informing current practice in these two areas.Pleural infection and malignancy are amongst the most common causes of pleural disease and form the mainstay of pleural practice. There has been significant increase in scientific understanding in these areas in the last decade. https://bit.ly/2zOV0KE