RT Journal Article
SR Electronic
T1 Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020)
JF European Respiratory Review
JO EUROPEAN RESPIRATORY REVIEW
FD European Respiratory Society
SP 200287
DO 10.1183/16000617.0287-2020
VO 29
IS 157
A1 Chunxue Bai
A1 Sanjay H. Chotirmall
A1 Jordi Rello
A1 George A. Alba
A1 Leo C. Ginns
A1 Jerry A. Krishnan
A1 Robert Rogers
A1 Elisabeth Bendstrup
A1 Pierre-Regis Burgel
A1 James D. Chalmers
A1 Abigail Chua
A1 Kristina A. Crothers
A1 Abhijit Duggal
A1 Yeon Wook Kim
A1 John G. Laffey
A1 Carlos M. Luna
A1 Michael S. Niederman
A1 Ganesh Raghu
A1 Julio A. Ramirez
A1 Jordi Riera
A1 Oriol Roca
A1 Maximiliano Tamae-Kakazu
A1 Antoni Torres
A1 Richard R. Watkins
A1 Miriam Barrecheguren
A1 Mirko Belliato
A1 Hassan A. Chami
A1 Rongchang Chen
A1 Gustavo A. Cortes-Puentes
A1 Charles Delacruz
A1 Margaret M. Hayes
A1 Leo M.A. Heunks
A1 Steven R. Holets
A1 Catherine L. Hough
A1 Sugeet Jagpal
A1 Kyeongman Jeon
A1 Takeshi Johkoh
A1 May M. Lee
A1 Janice Liebler
A1 Gerry N. McElvaney
A1 Ari Moskowitz
A1 Richard A. Oeckler
A1 Iñigo Ojanguren
A1 Anthony O'Regan
A1 Mathias W. Pletz
A1 Chin Kook Rhee
A1 Marcus J. Schultz
A1 Enrico Storti
A1 Charlie Strange
A1 Carey C. Thomson
A1 Francesca J. Torriani
A1 Xun Wang
A1 Wim Wuyts
A1 Tao Xu
A1 Dawei Yang
A1 Ziqiang Zhang
A1 Kevin C. Wilson
YR 2020
UL http://err.ersjournals.com/content/29/157/200287.abstract
AB Background Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.Methods An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion.Results The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder.Conclusions The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.For patients with acute COVID-19 pneumonia who require oxygen support, the International Task Force made suggestions for remdesivir and dexamethasone, but against hydroxychloroquine. Post-discharge management of COVID-19 survivors is a research priority. https://bit.ly/32B96uI