TY - JOUR T1 - Pulmonary function testing in children's interstitial lung disease JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW DO - 10.1183/16000617.0019-2020 VL - 29 IS - 157 SP - 200019 AU - Astrid Madsen Ring AU - Julia Carlens AU - Andy Bush AU - Silvia Castillo-Corullón AU - Salvatore Fasola AU - Mirella Piera Gaboli AU - Matthias Griese AU - Vaclav Koucky AU - Stefania La Grutta AU - Enrico Lombardi AU - Marijke Proesmans AU - Nicolaus Schwerk AU - Deborah Snijders AU - Kim Gjerum Nielsen AU - Frederik Buchvald Y1 - 2020/09/30 UR - http://err.ersjournals.com/content/29/157/200019.abstract N2 - The use of pulmonary function tests (PFTs) has been widely described in airway diseases like asthma and cystic fibrosis, but for children's interstitial lung disease (chILD), which encompasses a broad spectrum of pathologies, the usefulness of PFTs is still undetermined, despite widespread use in adult interstitial lung disease. A literature review was initiated by the COST/Enter chILD working group aiming to describe published studies, to identify gaps in knowledge and to propose future research goals in regard to spirometry, whole-body plethysmography, infant and pre-school PFTs, measurement of diffusing capacity, multiple breath washout and cardiopulmonary exercise tests in chILD. The search revealed a limited number of papers published in the past three decades, of which the majority were descriptive and did not report pulmonary function as the main outcome.PFTs may be useful in different stages of management of children with suspected or confirmed chILD, but the chILD spectrum is diverse and includes a heterogeneous patient group in all ages. Research studies in well-defined patient cohorts are needed to establish which PFT and outcomes are most relevant for diagnosis, evaluation of disease severity and course, and monitoring individual conditions both for improvement in clinical care and as end-points in future randomised controlled trials.Pulmonary function testing may be useful in different stages of management of children with suspected or confirmed chILD but this literature search revealed only a limited number of papers published in the last three decades. https://bit.ly/3cs0uZr ER -