RT Journal Article
SR Electronic
T1 Pulmonary function testing in children's interstitial lung disease
JF European Respiratory Review
JO EUROPEAN RESPIRATORY REVIEW
FD European Respiratory Society
SP 200019
DO 10.1183/16000617.0019-2020
VO 29
IS 157
A1 Astrid Madsen Ring
A1 Julia Carlens
A1 Andy Bush
A1 Silvia Castillo-Corullón
A1 Salvatore Fasola
A1 Mirella Piera Gaboli
A1 Matthias Griese
A1 Vaclav Koucky
A1 Stefania La Grutta
A1 Enrico Lombardi
A1 Marijke Proesmans
A1 Nicolaus Schwerk
A1 Deborah Snijders
A1 Kim Gjerum Nielsen
A1 Frederik Buchvald
YR 2020
UL http://err.ersjournals.com/content/29/157/200019.abstract
AB The use of pulmonary function tests (PFTs) has been widely described in airway diseases like asthma and cystic fibrosis, but for children's interstitial lung disease (chILD), which encompasses a broad spectrum of pathologies, the usefulness of PFTs is still undetermined, despite widespread use in adult interstitial lung disease. A literature review was initiated by the COST/Enter chILD working group aiming to describe published studies, to identify gaps in knowledge and to propose future research goals in regard to spirometry, whole-body plethysmography, infant and pre-school PFTs, measurement of diffusing capacity, multiple breath washout and cardiopulmonary exercise tests in chILD. The search revealed a limited number of papers published in the past three decades, of which the majority were descriptive and did not report pulmonary function as the main outcome.PFTs may be useful in different stages of management of children with suspected or confirmed chILD, but the chILD spectrum is diverse and includes a heterogeneous patient group in all ages. Research studies in well-defined patient cohorts are needed to establish which PFT and outcomes are most relevant for diagnosis, evaluation of disease severity and course, and monitoring individual conditions both for improvement in clinical care and as end-points in future randomised controlled trials.Pulmonary function testing may be useful in different stages of management of children with suspected or confirmed chILD but this literature search revealed only a limited number of papers published in the last three decades. https://bit.ly/3cs0uZr