PT - JOURNAL ARTICLE AU - Radtke, Thomas AU - Crook, Sarah AU - Kaltsakas, Georgios AU - Louvaris, Zafeiris AU - Berton, Danilo AU - Urquhart, Don S. AU - Kampouras, Asterios AU - Rabinovich, Roberto A. AU - Verges, Samuel AU - Kontopidis, Dimitris AU - Boyd, Jeanette AU - Tonia, Thomy AU - Langer, Daniel AU - De Brandt, Jana AU - Goërtz, Yvonne M.J. AU - Burtin, Chris AU - Spruit, Martijn A. AU - Braeken, Dionne C.W. AU - Dacha, Sauwaluk AU - Franssen, Frits M.E. AU - Laveneziana, Pierantonio AU - Eber, Ernst AU - Troosters, Thierry AU - Neder, J. Alberto AU - Puhan, Milo A. AU - Casaburi, Richard AU - Vogiatzis, Ioannis AU - Hebestreit, Helge TI - ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases AID - 10.1183/16000617.0101-2018 DP - 2019 Dec 31 TA - European Respiratory Review PG - 180101 VI - 28 IP - 154 4099 - https://publications.ersnet.org//content/28/154/180101.short 4100 - https://publications.ersnet.org//content/28/154/180101.full SO - EUROPEAN RESPIRATORY REVIEW2019 Dec 31; 28 AB - The objective of this document was to standardise published cardiopulmonary exercise testing (CPET) protocols for improved interpretation in clinical settings and multicentre research projects. This document: 1) summarises the protocols and procedures used in published studies focusing on incremental CPET in chronic lung conditions; 2) presents standard incremental protocols for CPET on a stationary cycle ergometer and a treadmill; and 3) provides patients' perspectives on CPET obtained through an online survey supported by the European Lung Foundation. We systematically reviewed published studies obtained from EMBASE, Medline, Scopus, Web of Science and the Cochrane Library from inception to January 2017. Of 7914 identified studies, 595 studies with 26 523 subjects were included. The literature supports a test protocol with a resting phase lasting at least 3 min, a 3-min unloaded phase, and an 8- to 12-min incremental phase with work rate increased linearly at least every minute, followed by a recovery phase of at least 2–3 min. Patients responding to the survey (n=295) perceived CPET as highly beneficial for their diagnostic assessment and informed the Task Force consensus. Future research should focus on the individualised estimation of optimal work rate increments across different lung diseases, and the collection of robust normative data.The document facilitates standardisation of conducting, reporting and interpreting cardiopulmonary exercise tests in chronic lung diseases for comparison of reference data, multi-centre studies and assessment of interventional efficacy. http://bit.ly/31SXeB5