PT - JOURNAL ARTICLE AU - Marios Panagiotou AU - Alistair C. Church AU - Martin K. Johnson AU - Andrew J. Peacock TI - Pulmonary vascular and cardiac impairment in interstitial lung disease AID - 10.1183/16000617.0053-2016 DP - 2017 Mar 31 TA - European Respiratory Review PG - 160053 VI - 26 IP - 143 4099 - http://err.ersjournals.com/content/26/143/160053.short 4100 - http://err.ersjournals.com/content/26/143/160053.full SO - EUROPEAN RESPIRATORY REVIEW2017 Mar 31; 26 AB - Pulmonary vascular and cardiac impairment is increasingly appreciated as a major adverse factor in the natural history of interstitial lung disease. This clinically orientated review focuses on the current concepts in the pathogenesis, pathophysiology and implications of the detrimental sequence of increased pulmonary vascular resistance, pre-capillary pulmonary hypertension and right heart failure in interstitial lung disease, and provides guidance on its management.Development of pulmonary hypertension is a major adverse factor in the natural history of interstitial lung disease http://ow.ly/nJB0302XAmD