TY - JOUR T1 - Pulmonary manifestations of Sjögren's syndrome JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW SP - 110 LP - 123 DO - 10.1183/16000617.0011-2016 VL - 25 IS - 140 AU - Thomas Flament AU - Adrien Bigot AU - Benjamin Chaigne AU - Helene Henique AU - Elisabeth Diot AU - Sylvain Marchand-Adam Y1 - 2016/06/01 UR - http://err.ersjournals.com/content/25/140/110.abstract N2 - In 9–20% of cases, Sjögren's syndrome is associated with various respiratory symptoms. The most typical manifestations are chronic interstitial lung disease (ILD) and tracheobronchial disease. The most common manifestation of ILD is nonspecific interstitial pneumonia in its fibrosing variant. Other types of ILD, such as organising pneumonia, usual interstitial pneumonia and lymphocytic interstitial pneumonitis, are rare. Their radiological presentation is less distinctive, and definitive diagnosis may require the use of transbronchial or surgical lung biopsy. Corticosteroid therapy is the mainstay of ILD treatment in Sjögren's syndrome, but the use of other immunosuppressive drugs needs to be determined. ILD is a significant cause of death in Sjögren's syndrome. Tracheobronchial disease is common in Sjögren's syndrome, characterised by diffuse lymphocytic infiltration of the airway. It is sometimes responsible for a crippling chronic cough. It can also present in the form of bronchial hyperresponsiveness, bronchiectasis, bronchiolitis or recurrent respiratory infections. The management of these manifestations may require treatment for dryness and/or inflammation of the airways. Airway disease has little effect on respiratory function and is rarely the cause of death in Sjögren's syndrome patients. Rare respiratory complications such as amyloidosis, lymphoma or pulmonary hypertension should not be disregarded in Sjögren's syndrome patients.We present the features, diagnostic tests and treatments of thoracic manifestations of Sjögren's syndrome http://ow.ly/10m8vd ER -