PT - JOURNAL ARTICLE AU - Sophia Schiza AU - Charalampos Mermigkis AU - George A. Margaritopoulos AU - Zoi Daniil AU - Sergio Harari AU - Venerino Poletti AU - Elizabetta A. Renzoni AU - Olga Torre AU - Dina Visca AU - Isolde Bouloukaki AU - George Sourvinos AU - Katerina M. Antoniou TI - Idiopathic pulmonary fibrosis and sleep disorders: no longer strangers in the night AID - 10.1183/16000617.00009114 DP - 2015 Jun 01 TA - European Respiratory Review PG - 327--339 VI - 24 IP - 136 4099 - http://err.ersjournals.com/content/24/136/327.short 4100 - http://err.ersjournals.com/content/24/136/327.full SO - EUROPEAN RESPIRATORY REVIEW2015 Jun 01; 24 AB - The prevalence of obstructive sleep apnoea (OSA) is continuously increasing in patients with idiopathic pulmonary fibrosis (IPF) and, for the first time, the recent IPF guidelines recognise OSA as an important associated comorbidity that can affect patient's survival. Thus, it becomes conceivable that clinicians should refer patients with newly diagnosed IPF to sleep centres for the diagnosis and treatment of OSA as well as for addressing issues regarding the reduced compliance of patients with continuous positive airway pressure therapy. The discovery of biomarkers common to both disorders may help early diagnosis, institution of the most appropriate treatment and follow-up of patients. Better understanding of epigenetic changes may provide useful information about pathogenesis and, possibly, development of new drugs for a dismal disease like IPF. It is now believed that IPF and sleep disorders can coexist in the same patient http://ow.ly/LXPSL