TY - JOUR T1 - Bronchial rupture related to endobronchial stenting in relapsing polychondritis JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW SP - 367 LP - 369 DO - 10.1183/09059180.00000612 VL - 21 IS - 126 AU - Jeanne Chapron AU - Delphine Wermert AU - Françoise Le Pimpec-Barthes AU - Aurélie Cazes AU - Romain Pommier AU - Anne Hernigou AU - Jacques Lacronique AU - Daniel Dusser AU - Pierre-Régis Burgel Y1 - 2012/12/01 UR - http://err.ersjournals.com/content/21/126/367.abstract N2 - To the Editor:Relapsing polychondritis is a rare multi-systemic disease characterised by recurrent episodes of inflammation and destruction of cartilaginous structures [1]. Airway involvement by relapsing polychondritis, which results in tracheobronchomalacia and airway stenosis, is associated with a poor prognosis. Several reports have suggested that endobronchial intervention can be beneficial in these subjects [2, 3]. Herein, we describe a case of bronchial rupture related to endobronchial intervention in a patient with relapsing polychondritis.A 47-yr-old male nonsmoker was referred for management of progressive dyspnoea, stridor and cough evolving over 12 months. He had been considered to have severe asthma and was treated with a fixed combination of inhaled corticosteroids and long-acting β-agonists, and short courses of oral corticosteroids. Spirometry showed fixed airflow limitation with a post-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity of 22% and an FEV1 of 22% predicted. A thoracic computed tomography (CT) scan revealed marked thickening and narrowing of trachea and mainstem bronchi (fig. 1). A diagnosis of relapsing polychondritis was suggested; the patient had no auricular or nasal chondritis and no ocular symptoms. Fluorodeoxyglucose positron emission tomography showed no cartilaginous tracer uptake. Bronchoscopy showed marked thickening and inflammation of airway mucosa. Severe tracheobronchomalacia, … ER -