RT Journal Article SR Electronic T1 An official American Thoracic Society/European Respiratory Society statement: research questions in COPD JF European Respiratory Review JO EUROPEAN RESPIRATORY REVIEW FD European Respiratory Society SP 159 OP 172 DO 10.1183/16000617.00000315 VO 24 IS 136 A1 Celli, Bartolome R. A1 Decramer, Marc A1 Wedzicha, Jadwiga A. A1 Wilson, Kevin C. A1 Agustí, Alvar A. A1 Criner, Gerard J. A1 MacNee, William A1 Make, Barry J. A1 Rennard, Stephen I. A1 Stockley, Robert A. A1 Vogelmeier, Claus A1 Anzueto, Antonio A1 Au, David H. A1 Barnes, Peter J. A1 Burgel, Pierre-Regis A1 Calverley, Peter M. A1 Casanova, Ciro A1 Clini, Enrico M. A1 Cooper, Christopher B. A1 Coxson, Harvey O. A1 Dusser, Daniel J. A1 Fabbri, Leonardo M. A1 Fahy, Bonnie A1 Ferguson, Gary T. A1 Fisher, Andrew A1 Fletcher, Monica J. A1 Hayot, Maurice A1 Hurst, John R. A1 Jones, Paul W. A1 Mahler, Donald A. A1 Maltais, François A1 Mannino, David M. A1 Martinez, Fernando J. A1 Miravitlles, Marc A1 Meek, Paula M. A1 Papi, Alberto A1 Rabe, Klaus F. A1 Roche, Nicolas A1 Sciurba, Frank C. A1 Sethi, Sanjay A1 Siafakas, Nikos A1 Sin, Don D. A1 Soriano, Joan B. A1 Stoller, James K. A1 Tashkin, Donald P. A1 Troosters, Thierry A1 Verleden, Geert M. A1 Verschakelen, Johny A1 Vestbo, Jorgen A1 Walsh, John W. A1 Washko, George R. A1 Wise, Robert A. A1 Wouters, Emiel F.M. A1 ZuWallack, Richard L. YR 2015 UL https://publications.ersnet.org//content/24/136/159.abstract AB Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes. ATS/ERS statement highlighting research areas that will have the greatest impact on patient-centred outcomes in COPD http://ow.ly/LXW2J