PT  - JOURNAL ARTICLE
AU  - Bartolome R. Celli
AU  - Marc Decramer
AU  - Jadwiga A. Wedzicha
AU  - Kevin C. Wilson
AU  - Alvar A. Agustí
AU  - Gerard J. Criner
AU  - William MacNee
AU  - Barry J. Make
AU  - Stephen I. Rennard
AU  - Robert A. Stockley
AU  - Claus Vogelmeier
AU  - Antonio Anzueto
AU  - David H. Au
AU  - Peter J. Barnes
AU  - Pierre-Regis Burgel
AU  - Peter M. Calverley
AU  - Ciro Casanova
AU  - Enrico M. Clini
AU  - Christopher B. Cooper
AU  - Harvey O. Coxson
AU  - Daniel J. Dusser
AU  - Leonardo M. Fabbri
AU  - Bonnie Fahy
AU  - Gary T. Ferguson
AU  - Andrew Fisher
AU  - Monica J. Fletcher
AU  - Maurice Hayot
AU  - John R. Hurst
AU  - Paul W. Jones
AU  - Donald A. Mahler
AU  - François Maltais
AU  - David M. Mannino
AU  - Fernando J. Martinez
AU  - Marc Miravitlles
AU  - Paula M. Meek
AU  - Alberto Papi
AU  - Klaus F. Rabe
AU  - Nicolas Roche
AU  - Frank C. Sciurba
AU  - Sanjay Sethi
AU  - Nikos Siafakas
AU  - Don D. Sin
AU  - Joan B. Soriano
AU  - James K. Stoller
AU  - Donald P. Tashkin
AU  - Thierry Troosters
AU  - Geert M. Verleden
AU  - Johny Verschakelen
AU  - Jorgen Vestbo
AU  - John W. Walsh
AU  - George R. Washko
AU  - Robert A. Wise
AU  - Emiel F.M. Wouters
AU  - Richard L. ZuWallack
TI  - An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
AID  - 10.1183/16000617.00000315
DP  - 2015 Jun 01
TA  - European Respiratory Review
PG  - 159--172
VI  - 24
IP  - 136
4099  - http://err.ersjournals.com/content/24/136/159.short
4100  - http://err.ersjournals.com/content/24/136/159.full
SO  - EUROPEAN RESPIRATORY REVIEW2015 Jun 01; 24
AB  - Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes. ATS/ERS statement highlighting research areas that will have the greatest impact on patient-centred outcomes in COPD http://ow.ly/LXW2J