RT Journal Article
SR Electronic
T1 Comorbidities of COPD
JF European Respiratory Review
JO EUROPEAN RESPIRATORY REVIEW
FD European Respiratory Society
SP 454
OP 475
DO 10.1183/09059180.00008612
VO 22
IS 130
A1 Cavaillès, Arnaud
A1 Brinchault-Rabin, Graziella
A1 Dixmier, Adrien
A1 Goupil, François
A1 Gut-Gobert, Christophe
A1 Marchand-Adam, Sylvain
A1 Meurice, Jean-Claude
A1 Morel, Hugues
A1 Person-Tacnet, Christine
A1 Leroyer, Christophe
A1 Diot, Patrice
YR 2013
UL https://publications.ersnet.org//content/22/130/454.abstract
AB By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality. Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco smoking is a common risk factor for many comorbidities, including coronary heart disease, heart failure and lung cancer. Comorbidities such as pulmonary artery disease and malnutrition are directly caused by COPD, whereas others, such as systemic venous thromboembolism, anxiety, depression, osteoporosis, obesity, metabolic syndrome, diabetes, sleep disturbance and anaemia, have no evident physiopathological relationship with COPD. The common ground between most of these extrapulmonary manifestations is chronic systemic inflammation. All of these diseases potentiate the morbidity of COPD, leading to increased hospitalisations and healthcare costs. They can frequently cause death, independently of respiratory failure. Comorbidities make the management of COPD difficult and need to be evaluated and treated adequately.