TY - JOUR T1 - Association of pulmonary aspergilloma and allergic bronchopulmonary aspergillosis JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW SP - 349 LP - 351 DO - 10.1183/09059180.00004810 VL - 19 IS - 118 AU - D. Montani AU - I. Zendah AU - L. Achouh AU - P. Dorfmuller AU - O. Mercier AU - G. Garcia AU - M. Humbert Y1 - 2010/12/01 UR - http://err.ersjournals.com/content/19/118/349.abstract N2 - To the Editors:We have read with interest recent reports on the complex interactions between Aspergillus fumigatus and the lungs [1–3]. A. fumigatus may be involved in different respiratory diseases including aspergilloma, allergic bronchopulmonary aspergillosis (ABPA) or invasive infectious manifestations. However, these different manifestations are usually not concomitantly present and there are only a few studies that report the association between these complications [4–14]. We wish to present a case of fully documented aspergilloma and ABPA in a patient with difficult asthma, which represented a difficult therapeutic challenge.A 50-yr-old female, nonsmoker was followed up since 2000 for difficult to control non-atopic asthma associated with severe rhinosinusitis. In March 2008, the patient presented to the respiratory department (Hôpital Antonie Béclère, Clamart, France) with a 1-month history of mild recurrent haemoptysis. Physical examination was normal. Chest radiography showed excavated lung opacity in the superior left field. A thoracic computed tomography (CT) scan revealed a cavity with a fungus ball in the left upper lobe and two other opacities in the left lower lobe (fig. 1). There was no fungus ball in the sinuses. … ER -