TY - JOUR T1 - Winners of the ERS Annual Awards 2006 JF - European Respiratory Review JO - EUROPEAN RESPIRATORY REVIEW SP - 165 LP - 167 DO - 10.1183/09059180.00010107 VL - 15 IS - 101 AU - P. S. Burge AU - V. C. Moore Y1 - 2006/12/01 UR - http://err.ersjournals.com/content/15/101/165.abstract N2 - The European Respiratory Review (ERR) is delighted to publish articles from winners of European Respiratory Society (ERS) Annual Awards 2006. The awardees were invited to include the background of their work, how they thought it might be important to respiratory medicine, the aims of the team in which they work and to include their award-winning abstract. The articles encompass a spectrum of research and have been split into three sections, presenting scientific articles in the first and third sections, and clinical articles in the second section. They provide an insight into research being carried out around the world today. The first chapter presents Dr Stephen A. Renshaw's research: “The molecular controls of resolution of inflammation: what can we learn from zebrafish?” (page 168). His PhD thesis explored a family of death receptors on neutrophil surfaces and their signalling pathways. This became difficult in human neutrophils, so the zebrafish has now become the in vivo model for resolving inflammation, as it shares many features of the human immune system and has helped the team to generate fluorescent systems for the easy visualisation of neutrophilic inflammation in vivo. Dr Emma H. Baker's primary research focus is on respiratory epithelial transport processes, but through collaboration with Dr Peterson, she undertook the study entitled “Development of a biomarker for lung inflammation in COPD [chronic obstructive pulmonary disease] through analysis of labelled leukocyte transit through the lung circulation” (page 170), investigating the ratio of the downslope of curve in the lungs compared with the heart. She found a significantly smaller ratio in stable COPD patients compared to controls. Dr Hajime Yoshisue worked at the University of Southampton's School of Medicine, Southampton, UK, on his project entitled “Molecular mechanisms of the synergy between cysteinyl-leukotrienes and receptor tyrosine kinase growth factors on human bronchial fibroblast proliferation” … ER -