PT  - JOURNAL ARTICLE
AU  - Pierre-Régis Burgel
AU  - Anne Bergeron
AU  - Jacques de Blic
AU  - Philippe Bonniaud
AU  - Arnaud Bourdin
AU  - Pascal Chanez
AU  - Thierry Chinet
AU  - Jean-Charles Dalphin
AU  - Philippe Devillier
AU  - Antoine Deschildre
AU  - Alain Didier
AU  - Marianne Kambouchner
AU  - Christiane Knoop
AU  - François Laurent
AU  - Hilario Nunes
AU  - Thierry Perez
AU  - Nicolas Roche
AU  - Isabelle Tillie-Leblond
AU  - Daniel Dusser
TI  - Small airways diseases, excluding asthma and COPD: an overview
AID  - 10.1183/09059180.00001313
DP  - 2013 Jun 01
TA  - European Respiratory Review
PG  - 131--147
VI  - 22
IP  - 128
4099  - http://err.ersjournals.com/content/22/128/131.short
4100  - http://err.ersjournals.com/content/22/128/131.full
SO  - EUROPEAN RESPIRATORY REVIEW2013 Jun 01; 22
AB  - This review is the summary of a workshop on small airways disease, which took place in Porquerolles, France in November 2011. The purpose of this workshop was to review the evidence on small airways (bronchiolar) involvement under various pathophysiological circumstances, excluding asthma and chronic obstructive pulmonary disease. Histopathological patterns associated with small airways disease were reviewed, including cellular and obliterative bronchiolitis. Many pathophysiological conditions have been associated with small airways disease including airway infections, connective tissue diseases and inflammatory bowel diseases, bone marrow and lung transplantation, common variable immunodeficiency disorders, diffuse panbronchiolitis, and diseases related to environmental exposures to pollutants, allergens and drugs. Pathogenesis, clinical presentation, a computed tomography scan and pulmonary function test findings are reviewed, and therapeutic options are described with the objective of providing an integrative approach to these disorders.