RT Journal Article
SR Electronic
T1 Bronchoscopic lung volume reduction
JF European Respiratory Review
JO EUROPEAN RESPIRATORY REVIEW
FD European Respiratory Society
SP 99
OP 103
DO 10.1183/09059180.00010009
VO 15
IS 100
A1 M. I. Polkey
A1 N. S. Hopkinson
YR 2006
UL http://err.ersjournals.com/content/15/100/99.abstract
AB Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of ∼25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed endobronchially and the creation of extrapulmonary pathways. Preliminary data from the former approach suggest that it can be successful and that the magnitude of success is related to reduction in dynamic hyperinflation.