PT - JOURNAL ARTICLE AU - M. I. Polkey AU - N. S. Hopkinson TI - Bronchoscopic lung volume reduction AID - 10.1183/09059180.00010009 DP - 2006 Dec 01 TA - European Respiratory Review PG - 99--103 VI - 15 IP - 100 4099 - http://err.ersjournals.com/content/15/100/99.short 4100 - http://err.ersjournals.com/content/15/100/99.full SO - EUROPEAN RESPIRATORY REVIEW2006 Dec 01; 15 AB - Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of ∼25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed endobronchially and the creation of extrapulmonary pathways. Preliminary data from the former approach suggest that it can be successful and that the magnitude of success is related to reduction in dynamic hyperinflation.