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Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis

Annelies L. Robijn, Marleen P. Bokern, Megan E. Jensen, Daniel Barker, Katherine J. Baines, Vanessa E. Murphy
European Respiratory Review 2022 31: 220039; DOI: 10.1183/16000617.0039-2022
Annelies L. Robijn
1School of Medicine and Public Health, College of Health, Medicine and Wellbeing, Priority Research Centre for Healthy Lungs, University of Newcastle, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia
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Marleen P. Bokern
2Dept of Pharmaco-Therapy, Epidemiology and Economics, University of Groningen, Groningen, The Netherlands
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Megan E. Jensen
1School of Medicine and Public Health, College of Health, Medicine and Wellbeing, Priority Research Centre for Healthy Lungs, University of Newcastle, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia
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Daniel Barker
3School of Medicine and Public Health, University of Newcastle, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia
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Katherine J. Baines
1School of Medicine and Public Health, College of Health, Medicine and Wellbeing, Priority Research Centre for Healthy Lungs, University of Newcastle, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia
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Vanessa E. Murphy
1School of Medicine and Public Health, College of Health, Medicine and Wellbeing, Priority Research Centre for Healthy Lungs, University of Newcastle, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia
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  • ORCID record for Vanessa E. Murphy
  • For correspondence: vanessa.murphy@newcastle.edu.au
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    FIGURE 1

    Flow diagram of included studies.

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    FIGURE 2

    Forest plots of meta-analyses. a) Age, b) obesity and c) smoking status. Exa: exacerbation.

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    FIGURE 3

    Forest plots of meta-analyses. a) Gestational weight gain, b) parity and c) plurality. Exa: exacerbation.

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    FIGURE 4

    Forest plots of meta-analyses. a) Asthma severity, b) history of recent hospitalisation/emergency department visit for asthma and c) inhaled corticosteroid (ICS) use ∼18 weeks’ gestation. Exa: exacerbation; MS: MarketScan (private insurance); MAX: Medicaid Analytic Extract (public insurance).

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European Respiratory Review: 31 (164)
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Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis
Annelies L. Robijn, Marleen P. Bokern, Megan E. Jensen, Daniel Barker, Katherine J. Baines, Vanessa E. Murphy
European Respiratory Review Jun 2022, 31 (164) 220039; DOI: 10.1183/16000617.0039-2022

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Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis
Annelies L. Robijn, Marleen P. Bokern, Megan E. Jensen, Daniel Barker, Katherine J. Baines, Vanessa E. Murphy
European Respiratory Review Jun 2022, 31 (164) 220039; DOI: 10.1183/16000617.0039-2022
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