Tables
- TABLE 1
Patient, intervention, comparison, outcome (PICO) questions
Question Population Intervention Comparison Outcome Recommendation PICO 1 In adult obese patients with OSA, should laparoscopic RYGB surgery or weight-reducing diet be used? Obese patients with OSA Laparoscopic RYGB surgery Weight-reducing diet AHI; sleep efficiency; health-related quality of life; sleepiness; hypertension; compliance; adverse events Conditional recommendation for the intervention, very low quality of evidence PICO 2 Should a custom-made dual-block mandibular advancement device or CPAP be used for adult patients with OSA? Adult patients with OSA Custom-made dual-block mandibular advancement device CPAP AHI; sleep efficiency; oxygen desaturation; sleepiness; physical functioning; arterial hypertension; compliance; adverse events Conditional recommendation against the intervention, very low quality of evidence PICO 3 Should hypoglossal nerve stimulation during sleep or no treatment be used for adult patients with OSA? Adult patients with OSA Hypoglossal nerve stimulation No treatment AHI; sleep efficiency; oxygen desaturation; sleepiness; physical functioning; arterial hypertension; compliance; adverse events Conditional recommendation against the intervention, very low quality of evidence PICO 4a In adult patients with OSA, should myofunctional therapy or no treatment be used? Adult patients with OSA Myofunctional therapy No treatment AHI; sleep efficiency; sleepiness; physical functioning; compliance; adverse events Conditional recommendation for either the intervention or the comparison, low quality of evidence PICO 4b Should myofunctional therapy or CPAP be used for adult patients with OSA? Adult patients with OSA Myofunctional therapy CPAP AHI; sleep efficiency; sleepiness; physical functioning; compliance; adverse events Conditional recommendation against the intervention, low quality of evidence PICO 5 Should maxillo-mandibular osteotomy or CPAP be used for adult patients with OSA? Adult patients with OSA Maxillo-mandibular osteotomy CPAP AHI; sleepiness; satisfaction; adverse events Conditional recommendation for either the intervention or the comparison, very low quality of evidence PICO 6 Should carbonic anhydrase inhibitors (compared to placebo) be used for adult patients with OSA? Adult patients with OSA Carbonic anhydrase inhibitors Placebo AHI; sleep efficiency; oxygen desaturation; sleepiness; arterial hypertension; compliance; adverse events Conditional recommendation for the intervention, low quality of evidence PICO 7 Should positional therapy or CPAP be used for adult patients with position-dependent OSA? Adult patients with position-dependent OSA Positional therapy CPAP AHI; sleep efficiency; oxygen desaturation; sleepiness; health-related quality of life; energy level scores; compliance; adverse events Conditional recommendation for either the intervention or the comparison, very low certainty of evidence PICO 8 Should positional therapy (intervention) or custom made dual-block mandibular advancement devices (control) be used for adult patients with position-dependent OSA? Adult patients with position-dependent OSA Positional therapy Custom-made dual-block mandibular advancement device AHI; sleep efficiency; oxygen desaturation; sleepiness; arterial hypertension; adherence; adverse events; quality of life Conditional recommendation for either the intervention or the comparison, very low certainty of evidence OSA: obstructive sleep apnoea; RYGB: Roux-en-Y gastric bypass; AHI: apnoea–hypopnoea index; CPAP: continuous positive airway pressure.
Supplementary Materials
Supplementary Material
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Supplementary material ERR-0200-2021.SUPPLEMENT
Vol 30 Issue 162
Table of Contents
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
