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Antifibrotic drugs in lung transplantation and chronic lung allograft dysfunction: a review

Saskia Bos, Laurens J. De Sadeleer, Arno Vanstapel, Hanne Beeckmans, Annelore Sacreas, Jonas Yserbyt, Wim A. Wuyts, Robin Vos
European Respiratory Review 2021 30: 210050; DOI: 10.1183/16000617.0050-2021
Saskia Bos
1Dept of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
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  • For correspondence: saskia.bos@uzleuven.be
Laurens J. De Sadeleer
2Dept of Respiratory Diseases, Ziekenhuis Oost-Limburg, Genk, Belgium
3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
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Arno Vanstapel
3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
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Hanne Beeckmans
4Dept of Internal Medicine, University Hospitals Leuven, Leuven, Belgium
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  • ORCID record for Hanne Beeckmans
Annelore Sacreas
3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
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Jonas Yserbyt
1Dept of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
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Wim A. Wuyts
1Dept of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
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Robin Vos
1Dept of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
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Article Information

vol. 30 no. 160
DOI 
https://doi.org/10.1183/16000617.0050-2021
PubMed 
34415849

Published By 
European Respiratory Society
Print ISSN 
0905-9180
Online ISSN 
1600-0617
History 
  • Received February 25, 2021
  • Accepted April 2, 2021
  • Published online June 1, 2021.

Copyright & Usage 
Copyright ©The authors 2021 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Saskia Bos1⇑,
  2. Laurens J. De Sadeleer2,3,
  3. Arno Vanstapel3,
  4. Hanne Beeckmans4,
  5. Annelore Sacreas3,
  6. Jonas Yserbyt1,3,
  7. Wim A. Wuyts1,3 and
  8. Robin Vos1,3
  1. 1Dept of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
  2. 2Dept of Respiratory Diseases, Ziekenhuis Oost-Limburg, Genk, Belgium
  3. 3Dept of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
  4. 4Dept of Internal Medicine, University Hospitals Leuven, Leuven, Belgium
  1. Corresponding author: Saskia Bos (saskia.bos{at}uzleuven.be)
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Vol 30 Issue 160 Table of Contents
European Respiratory Review: 30 (160)
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Antifibrotic drugs in lung transplantation and chronic lung allograft dysfunction: a review
Saskia Bos, Laurens J. De Sadeleer, Arno Vanstapel, Hanne Beeckmans, Annelore Sacreas, Jonas Yserbyt, Wim A. Wuyts, Robin Vos
European Respiratory Review Jun 2021, 30 (160) 210050; DOI: 10.1183/16000617.0050-2021

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Antifibrotic drugs in lung transplantation and chronic lung allograft dysfunction: a review
Saskia Bos, Laurens J. De Sadeleer, Arno Vanstapel, Hanne Beeckmans, Annelore Sacreas, Jonas Yserbyt, Wim A. Wuyts, Robin Vos
European Respiratory Review Jun 2021, 30 (160) 210050; DOI: 10.1183/16000617.0050-2021
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Jump To

  • Article
    • Abstract
    • Abstract
    • Introduction
    • Pirfenidone and nintedanib: two key antifibrotic drugs
    • Antifibrotics in IPF
    • Antifibrotics in non-IPF progressive fibrosing ILD
    • Antifibrotics in ILD patients referred for LTx
    • Mechanisms of antifibrotics on the pathophysiological processes after LTx and in CLAD development
    • Antifibrotics in CLAD phenotype BOS
    • Antifibrotics in CLAD phenotype RAS
    • Future areas of interest
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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  • Interstitial and orphan lung disease
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