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Cystic fibrosis-related diabetes and lung disease: an update

Bernadette J. Prentice, Adam Jaffe, Shihab Hameed, Charles F. Verge, Shafagh Waters, John Widger
European Respiratory Review 2021 30: 200293; DOI: 10.1183/16000617.0293-2020
Bernadette J. Prentice
1Dept of Respiratory Medicine, Sydney Children's Hospital, Randwick, Australia
2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
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  • ORCID record for Bernadette J. Prentice
  • For correspondence: Bernadette.prentice@health.nsw.gov.au
Adam Jaffe
1Dept of Respiratory Medicine, Sydney Children's Hospital, Randwick, Australia
2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
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Shihab Hameed
2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
3Faculty of Medicine, University of Sydney, Sydney, Australia
4Dept of Endocrinology, Sydney Children's Hospital, Randwick, Australia
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Charles F. Verge
2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
4Dept of Endocrinology, Sydney Children's Hospital, Randwick, Australia
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Shafagh Waters
2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
5MiCF Research Centre, Sydney, Australia
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  • ORCID record for Shafagh Waters
John Widger
1Dept of Respiratory Medicine, Sydney Children's Hospital, Randwick, Australia
2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
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Article Information

vol. 30 no. 159
DOI 
https://doi.org/10.1183/16000617.0293-2020
PubMed 
33597125

Published By 
European Respiratory Society
Print ISSN 
0905-9180
Online ISSN 
1600-0617
History 
  • Received September 4, 2020
  • Accepted November 13, 2020
  • Published online February 16, 2021.

Copyright & Usage 
Copyright ©ERS 2021 This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

Author Information

  1. Bernadette J. Prentice1,2⇑,
  2. Adam Jaffe1,2,
  3. Shihab Hameed2,3,4,
  4. Charles F. Verge2,4,
  5. Shafagh Waters2,5 and
  6. John Widger1,2
  1. 1Dept of Respiratory Medicine, Sydney Children's Hospital, Randwick, Australia
  2. 2School of Women's and Children's Health, University of New South Wales, Sydney, Randwick, Australia
  3. 3Faculty of Medicine, University of Sydney, Sydney, Australia
  4. 4Dept of Endocrinology, Sydney Children's Hospital, Randwick, Australia
  5. 5MiCF Research Centre, Sydney, Australia
  1. Correspondence: Bernadette Prentice, Dept of Respiratory Medicine, Sydney Children's Hospital, High St, Randwick, NSW 2031, Australia. E-mail: Bernadette.prentice{at}health.nsw.gov.au
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Vol 30 Issue 159 Table of Contents
European Respiratory Review: 30 (159)
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Cystic fibrosis-related diabetes and lung disease: an update
Bernadette J. Prentice, Adam Jaffe, Shihab Hameed, Charles F. Verge, Shafagh Waters, John Widger
European Respiratory Review Mar 2021, 30 (159) 200293; DOI: 10.1183/16000617.0293-2020

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Cystic fibrosis-related diabetes and lung disease: an update
Bernadette J. Prentice, Adam Jaffe, Shihab Hameed, Charles F. Verge, Shafagh Waters, John Widger
European Respiratory Review Mar 2021, 30 (159) 200293; DOI: 10.1183/16000617.0293-2020
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  • Article
    • Abstract
    • Abstract
    • Introduction
    • Pathophysiology of CFRD
    • Clinical implications of CFRD
    • Diabetes and nutrition
    • Infection and hyperglycaemia
    • Hyperglycaemia and the pulmonary microbiome
    • Tissue damage
    • ASL acid–base balance
    • Hyperglycaemia and the effect on the inflammatory response
    • Immunomodulation
    • Receptor for advanced glycation end products
    • CFRD genetic modifiers and the relationship with lung disease
    • Future research avenues
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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