Skip to main content

Main menu

  • Home
  • Current issue
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • COVID-19 submission information
    • Institutional open access agreements
    • Peer reviewer login
  • Alerts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • COVID-19 submission information
    • Institutional open access agreements
    • Peer reviewer login
  • Alerts
  • Subscriptions

Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis

Franck F. Rahaghi, Robert P. Baughman, Lesley Ann Saketkoo, Nadera J. Sweiss, Joseph B. Barney, Surinder S. Birring, Ulrich Costabel, Elliott D. Crouser, Marjolein Drent, Alicia K. Gerke, Jan C. Grutters, Nabeel Y. Hamzeh, Isham Huizar, W. Ennis James IV, Sanjay Kalra, Susanna Kullberg, Huiping Li, Elyse E. Lower, Lisa A. Maier, Mehdi Mirsaeidi, Joachim Müller-Quernheim, Eva M. Carmona Porquera, Lobelia Samavati, Dominique Valeyre, Mary Beth Scholand
European Respiratory Review 2020 29: 190146; DOI: 10.1183/16000617.0146-2019
Franck F. Rahaghi
1Cleveland Clinic Florida, Weston, FL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert P. Baughman
2University of Cincinnati Medical Center, Cincinnati, OH, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: baughmrp@ucmail.uc.edu
Lesley Ann Saketkoo
3Tulane University School of Medicine, New Orleans, LA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nadera J. Sweiss
4University of Illinois at Chicago College of Medicine, Chicago, IL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Nadera J. Sweiss
Joseph B. Barney
5University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Surinder S. Birring
6King's College Hospital, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ulrich Costabel
7Ruhrlandklinik, Essen, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elliott D. Crouser
8The Ohio State University, Wexner Medical Center, Columbus, OH, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marjolein Drent
9ILD Center of Excellence, St. Antonius Hospital, Nieuwegein, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alicia K. Gerke
10University of Iowa Carver College of Medicine, Iowa City, IA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jan C. Grutters
9ILD Center of Excellence, St. Antonius Hospital, Nieuwegein, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nabeel Y. Hamzeh
10University of Iowa Carver College of Medicine, Iowa City, IA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Isham Huizar
11Texas Tech University, Health Sciences Center, Lubbock, TX, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W. Ennis James IV
12Medical University of South Carolina College of Medicine, Charleston, SC, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sanjay Kalra
13Mayo Clinic, Rochester, MN, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Susanna Kullberg
14Karolinska University Hospital, Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Huiping Li
15Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Huiping Li
Elyse E. Lower
2University of Cincinnati Medical Center, Cincinnati, OH, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lisa A. Maier
16National Jewish Health, Denver, CO, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mehdi Mirsaeidi
17University of Miami Miller School of Medicine, Miami, FL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joachim Müller-Quernheim
18University Hospital Freiburg, Freiburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eva M. Carmona Porquera
13Mayo Clinic, Rochester, MN, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lobelia Samavati
19Wayne State University School of Medicine, Detroit, MI, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dominique Valeyre
20University of Paris-Nord, Saint-Denis, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mary Beth Scholand
21University of Utah Medical Center, Salt Lake City, UT, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Figures

  • Tables
  • Supplementary Materials
  • FIGURE 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 1

    The modified Delphi process used in the study.

  • FIGURE 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 2

    Delphi consensus for initial therapy and adjustments in therapy of pulmonary sarcoidosis. Bold indicates statements that reached consensus. #: dose decrease to find the lowest dose that provides satisfactory symptom relief and disease control.

  • FIGURE 3
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 3

    Likert scale consensus scores on use of selected non-biologic immunomodulators and biologic therapies. Bold indicates statements that reached consensus. MTX: methotrexate.

  • FIGURE 4
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 4

    Treatment algorithm for symptomatic or organ-threatening sarcoidosis derived from the Delphi consensus recommendations. MTX: methotrexate; TNF-α: tumour necrosis factor-α; CLEAR: concomitant levofloxacin, ethambutol, azithromycin and rifampin; RCI: repository corticotrophin injection. #: consider hydroxychloroquine in cases of hypercalcemia or skin disease; ¶: alternatives considered that did not reach consensus: azathioprine, mycophenolate, leflunomide; +: alternatives considered that did not reach consensus: adalimumab, rituximab.

Tables

  • Figures
  • Supplementary Materials
  • TABLE 1

    Characteristics of the Delphi panellists

    CharacteristicPanellists n
    Specialty#
     Pulmonology19
     Critical care3
     Rheumatology2
     Cardiology1
     Oncology1
    Experience treating sarcoidosis¶
     6–10 years5
     11–20 years8
     >20 years8
    Patients with sarcoidosis treated in entire career¶
     ≤5007
     501–10008
     1001–30003
     >30002
    Patients with sarcoidosis treated last year¶
     ≤507
     51–1008
     101–3003
     >3002

    #: highest degree of specialty is reported; ¶: some panellists did not respond to these questions.

    Supplementary Materials

    • Figures
    • Tables
    • Supplementary Material

      Please note: supplementary material is not edited by the Editorial Office, and is uploaded as it has been supplied by the author.

      Supplementary_appendix ERR-0146-2019_Supplementary_appendix

    PreviousNext
    Back to top
    View this article with LENS
    Vol 29 Issue 155 Table of Contents
    European Respiratory Review: 29 (155)
    • Table of Contents
    • Index by author
    Email

    Thank you for your interest in spreading the word on European Respiratory Society .

    NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

    Enter multiple addresses on separate lines or separate them with commas.
    Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis
    (Your Name) has sent you a message from European Respiratory Society
    (Your Name) thought you would like to see the European Respiratory Society web site.
    CAPTCHA
    This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
    Print
    Citation Tools
    Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis
    Franck F. Rahaghi, Robert P. Baughman, Lesley Ann Saketkoo, Nadera J. Sweiss, Joseph B. Barney, Surinder S. Birring, Ulrich Costabel, Elliott D. Crouser, Marjolein Drent, Alicia K. Gerke, Jan C. Grutters, Nabeel Y. Hamzeh, Isham Huizar, W. Ennis James, Sanjay Kalra, Susanna Kullberg, Huiping Li, Elyse E. Lower, Lisa A. Maier, Mehdi Mirsaeidi, Joachim Müller-Quernheim, Eva M. Carmona Porquera, Lobelia Samavati, Dominique Valeyre, Mary Beth Scholand
    European Respiratory Review Mar 2020, 29 (155) 190146; DOI: 10.1183/16000617.0146-2019

    Citation Manager Formats

    • BibTeX
    • Bookends
    • EasyBib
    • EndNote (tagged)
    • EndNote 8 (xml)
    • Medlars
    • Mendeley
    • Papers
    • RefWorks Tagged
    • Ref Manager
    • RIS
    • Zotero

    Share
    Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis
    Franck F. Rahaghi, Robert P. Baughman, Lesley Ann Saketkoo, Nadera J. Sweiss, Joseph B. Barney, Surinder S. Birring, Ulrich Costabel, Elliott D. Crouser, Marjolein Drent, Alicia K. Gerke, Jan C. Grutters, Nabeel Y. Hamzeh, Isham Huizar, W. Ennis James, Sanjay Kalra, Susanna Kullberg, Huiping Li, Elyse E. Lower, Lisa A. Maier, Mehdi Mirsaeidi, Joachim Müller-Quernheim, Eva M. Carmona Porquera, Lobelia Samavati, Dominique Valeyre, Mary Beth Scholand
    European Respiratory Review Mar 2020, 29 (155) 190146; DOI: 10.1183/16000617.0146-2019
    del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
    Full Text (PDF)

    Jump To

    • Article
      • Abstract
      • Abstract
      • Introduction
      • Methods
      • Results
      • Discussion
      • Conclusion
      • Supplementary material
      • Footnotes
      • References
    • Figures & Data
    • Info & Metrics
    • PDF

    Subjects

    • Interstitial and orphan lung disease
    • Tweet Widget
    • Facebook Like
    • Google Plus One

    More in this TOC Section

    • Mucolytics for acute exacerbations of COPD: a meta-analysis
    • Targeting IL-33 and TSLP pathways for novel pulmonary therapeutics
    • Physical activity promotion interventions in chronic airways disease
    Show more Reviews

    Related Articles

    Navigate

    • Home
    • Current issue
    • Archive

    About the ERR

    • Journal information
    • Editorial board
    • Reviewers
    • Press
    • Permissions and reprints
    • Advertising
    • Sponsorship

    The European Respiratory Society

    • Society home
    • myERS
    • Privacy policy
    • Accessibility

    ERS publications

    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS books online
    • ERS Bookshop

    Help

    • Feedback

    For authors

    • Instructions for authors
    • Publication ethics and malpractice
    • Submit a manuscript

    For readers

    • Alerts
    • Subjects
    • RSS

    Subscriptions

    • Accessing the ERS publications

    Contact us

    European Respiratory Society
    442 Glossop Road
    Sheffield S10 2PX
    United Kingdom
    Tel: +44 114 2672860
    Email: journals@ersnet.org

    ISSN

    Print ISSN: 0905-9180
    Online ISSN: 1600-0617

    Copyright © 2023 by the European Respiratory Society