Dyspnoea |
SOBQ [27] | Self-administered rating of dyspnoea associated with activities of daily living | 24 | 21 items assess severity of shortness of breath during specific activities of daily life; three additional items ask about limitations due to: shortness of breath, fear of harm from overexertion and fear of shortness of breath | | |
mMRC [28] | Assesses the severity of functional dyspnoea using a graded system (grade 0 (not troubled with breathlessness) to grade 4 (too breathless to leave the house)) | 1 | | | Quick, easy tool for use in daily practice; relates to disease progression |
BDI-TDI [29] | BDI: interviewer-administered rating of severity of dyspnoea at a single state, it provides a multidimensional measurement of dyspnoea based on three components that evoke dyspnoea in activities of daily living, in symptomatic individuals TDI: measures changes in dyspnoea severity from the baseline established by the BDI | 24 | BDI: functional impairment, magnitude of task, magnitude of effort; recall: during the past 2 weeks TDI: change in functional impairment, change in magnitude of task, change in magnitude of effort | Few specific instructions included in the instrument | Measures both baseline and change over time |
Borg Scale | Measures level of dyspnoea scored on a scale from 0 to 10 | | | Only measures dyspnoea during exertion, does not measure dyspnoea over time | Useful during 6-min walk test in daily practice |
FACIT-D [30, 31] | Evaluates dyspnoea severity | FACIT-D short form: 10 items FACIT-D long form: 33 items | Asking patients to evaluate their shortness of breath across a range of functional activities completed over a week | | Disease specific measure |
Cough |
LCQ [32] | Patient-reported questionnaire evaluating the impact of a cough on QoL | 19 | Three domains: physical, psychological and social | Limited experience in IPF Its specific nature may limit its usefulness when a broader assessment of QoL is desired, patients may need to complete multiple questionnaires if more comprehensive assessment is required | Reliable, responsive to changes, easy to complete |
CQLQ | Validated measure of cough-specific QoL | 28 | Six domains | Good validity for total score in IPF, but not for all domains | Comprehensive; responsive outcome measure |
Fatigue |
FAS [33] | General fatigue questionnaire | 10 | Questions reflect physical and mental fatigue | | Quick and easy to complete |
FACIT-FS [34] | Questionnaire to assess fatigue in patients with cancer | 13 | | Not specific for ILD | Reliable and valid scale |
Anxiety |
HADS [35] | Measures anxiety and depression in a general medical population | 14 | Comprises seven questions for anxiety and seven for depression | Should not be used as a diagnostic test; not originally developed in ILD | Reliable screening tool for anxiety and depression; simple and easy to use |
GAD-7 [36] | Measure of GAD | 7 | | Not specific to ILD | Valid and efficient tool for screening for GAD and assessing its severity in clinical practice and research |