The consequence of matrix dysfunction on lung immunity and the microbiome in COPD

Tracy Hussell; Sylvia Lui; Christopher Jagger; David Morgan; Oliver Brand

doi:10.1183/16000617.0032-2018

The consequence of matrix dysfunction on lung immunity and the microbiome in COPD

Tracy Hussell, Sylvia Lui, Christopher Jagger, David Morgan, Oliver Brand

European Respiratory Review 2018 27: 180032; DOI: 10.1183/16000617.0032-2018

Tracy Hussell

Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, UK

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Sylvia Lui

Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, UK

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Christopher Jagger

Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, UK

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David Morgan

Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, UK

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ORCID record for David Morgan

Oliver Brand

Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, UK

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FIGURE 1
Schematic illustration of the dominant changes in extracellular and basement membrane matrix from a) the healthy steady state to b) the development of chronic obstructive pulmonary disease.

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