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Advanced medical interventions in pleural disease

Rahul Bhatnagar, John P. Corcoran, Fabien Maldonado, David Feller-Kopman, Julius Janssen, Philippe Astoul, Najib M. Rahman
European Respiratory Review 2016 25: 199-213; DOI: 10.1183/16000617.0020-2016
Rahul Bhatnagar
1Academic Respiratory Unit, University of Bristol, Bristol, UK
9These authors contributed equally
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John P. Corcoran
2Oxford Centre for Respiratory Medicine, Oxford University Hospitals NHS Trust, Oxford, UK
3University of Oxford Respiratory Trials Unit, Churchill Hospital, Oxford, UK
9These authors contributed equally
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  • For correspondence: jpcorcoran@doctors.org.uk
Fabien Maldonado
4Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
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David Feller-Kopman
5Division of Pulmonary and Critical Care Medicine, John Hopkins University, Baltimore, MD, USA
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Julius Janssen
6Department of Pulmonary Diseases, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands
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Philippe Astoul
7Department of Thoracic Oncology, Pleural Diseases and Interventional Pulmonology, Hôpital Nord, Aix-Marseille University, Marseille, France
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Najib M. Rahman
2Oxford Centre for Respiratory Medicine, Oxford University Hospitals NHS Trust, Oxford, UK
3University of Oxford Respiratory Trials Unit, Churchill Hospital, Oxford, UK
8NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK
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  • FIGURE 1
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    FIGURE 1

    Nonexpandable lung. a) A single-use digital pleural manometer for use during thoracentesis. b) Pleural elastance curves representing normal, entrapped and trapped lung. Reproduced and modified from [13] with permission from the publisher. c) Chest radiograph demonstrating nonexpandable lung due to malignancy. A hydropneumothorax is visible at the left base with a large-bore chest drain in situ following thoracoscopy. The patient was treated with an indwelling pleural catheter.

  • FIGURE 2
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    FIGURE 2

    Examples of novel short-term drainage devices. a) 6-French thoracentesis catheter with integrated three-way tap. b) Chest drain bottle with integrated air leak monitor and digital suction. c) Pleural vent with integrated Heimlich valve for treatment of pneumothorax.

  • FIGURE 3
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    FIGURE 3

    Closed pleural biopsy. a) Example of a core-biopsy cutting needle. b) Example of procedural room set-up with operator line of sight and in-plane real-time ultrasound guidance. c) Ultrasound view of irregular parietal pleural thickening with effusion. d) Ultrasound view of irregular diaphragmatic and parietal pleural thickening with effusion. e) High-frequency (10 mHz) real-time ultrasound-guided cutting needle biopsy of pleural and chest wall mass. f) Low frequency (3.5 mHz) real-time ultrasound-guided cutting needle biopsy of parietal pleural thickening.

  • FIGURE 4
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    FIGURE 4

    Medical thoracoscopy. a) Example of procedural room set-up for rigid thoracoscopy. b) Normal parietal pleura with clearly defined anatomy. c) Pleural plaque disease with typical “fried-egg” appearance overlying ribs. d) Diffuse parietal and visceral pleural thickening secondary to mesothelioma with two-port strip biopsy technique. e) Heavily septated pleural space using two-port technique to divide septations in context of intercurrent malignancy and infection. f) Widespread malignant pleural nodularity with two-port biopsy technique.

Tables

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  • TABLE 1

    Indwelling pleural catheter (IPC) outcome data from series totalling more than 100 patients

    First author [ref.]YearTotal patients nEmpyema incidence %Pleurodesis incidence %Symptom improvement %Duration of IPC days
    Van Meter [64]201013702.845.695.651
    Rosenstengel [67]201210364.8NANANA
    Suzuki [68]2011418NA269144
    Mekhaiel [69]20122593.5n/an/a72
    Mullon [70]20111094.6599690
    Total 3192Mean 3.9Mean 43.5Mean 94.2Mean 64.3
    • The series by Van Meter [64] is a meta-analysis of 19 smaller studies. NA: not applicable.

Additional Files

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    Files in this Data Supplement:

    • D. Feller-Kopman
    • N.M. Rahman
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European Respiratory Review: 25 (140)
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Advanced medical interventions in pleural disease
Rahul Bhatnagar, John P. Corcoran, Fabien Maldonado, David Feller-Kopman, Julius Janssen, Philippe Astoul, Najib M. Rahman
European Respiratory Review Jun 2016, 25 (140) 199-213; DOI: 10.1183/16000617.0020-2016

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Advanced medical interventions in pleural disease
Rahul Bhatnagar, John P. Corcoran, Fabien Maldonado, David Feller-Kopman, Julius Janssen, Philippe Astoul, Najib M. Rahman
European Respiratory Review Jun 2016, 25 (140) 199-213; DOI: 10.1183/16000617.0020-2016
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  • Article
    • Abstract
    • Abstract
    • Introduction
    • Patient selection
    • Nonexpandable lung
    • Short-term drainage procedures
    • Indwelling pleural catheters
    • Medical thoracoscopy and closed pleural biopsy
    • Future directions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
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More in this TOC Section

Series

  • Supplemental oxygen and noninvasive ventilation
  • Nonpharmacological management of psychological distress in COPD
  • Lung transplantation for COPD/pulmonary emphysema
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Pleural diseases

  • Malignant pleural methothelioma: an update
  • Management of benign non-infective pleural effusion
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