Interstitial lung disease in systemic sclerosis: where do we stand?

Susanna Cappelli; Silvia Bellando Randone; Gianna Camiciottoli; Amato De Paulis; Serena Guiducci; Marco Matucci-Cerinic

doi:10.1183/16000617.00002915

Interstitial lung disease in systemic sclerosis: where do we stand?

Susanna Cappelli, Silvia Bellando Randone, Gianna Camiciottoli, Amato De Paulis, Serena Guiducci, Marco Matucci-Cerinic

European Respiratory Review 2015 24: 411-419; DOI: 10.1183/16000617.00002915

Susanna Cappelli

1Dept of Experimental and Clinical Medicine, Division of Rheumatology AOUC, School of Medicine, University of Florence, Florence, Italy

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For correspondence: susicappelli82@yahoo.it

Silvia Bellando Randone

1Dept of Experimental and Clinical Medicine, Division of Rheumatology AOUC, School of Medicine, University of Florence, Florence, Italy

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Gianna Camiciottoli

2Dept of Experimental and Clinical Medicine, Division of Pneumology and Lung Physiopathology AOUC, School of Medicine, University of Florence, Florence, Italy

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Amato De Paulis

3Dept of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy

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Serena Guiducci

1Dept of Experimental and Clinical Medicine, Division of Rheumatology AOUC, School of Medicine, University of Florence, Florence, Italy

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Marco Matucci-Cerinic

1Dept of Experimental and Clinical Medicine, Division of Rheumatology AOUC, School of Medicine, University of Florence, Florence, Italy

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FIGURE 1
Algorithm for diagnosis and follow-up of systemic sclerosis-interstitial lung disease (SSc-ILD). PFT: pulmonary function test; D_LCO: diffusing capacity of the lung for carbon monoxide; HRCT: high-resolution computed tomography.
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FIGURE 2
Algorithm to induce remission in systemic sclerosis-interstitial lung disease (SSc-ILD). HSCT: haematopoietic stem cell transplantation; CYC: cyclophosphamide; RTX: rituximab; AZA: azathioprine; MMF: mycophenolate mofetil.

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