Adverse childhood experience and asthma onset: a systematic review

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FIGURE 1
Flow chart depicting the article exclusion process.

TABLE 1

Reasons for exclusion of articles at stage 1 on the basis of titles and abstracts

Reason for exclusion at stage 1	Number of articles (%)
Focus on medical or physical environmental factors	302 (28)
Focus on conditions subsequent to development of asthma	163 (15)
Focus on adverse experience occurring in adult life	94 (9)
Does not follow prospective/longitudinal design	80 (7)
Focus on treatment interventions	192 (18)
Focus on adherence	57 (5)
Focus on diseases or conditions other than asthma	85 (8)
Focus on impact of health behaviours on asthma symptoms	48 (4)
Articles retained for further review	49 (5)
Total	1070 (100)

TABLE 2

Reasons for exclusion at stage 2 on the basis of full text articles

Reason for exclusion at stage 2	Number of articles (%)
*Adverse experience inadequately measured (e.g.* retrospectively)**	12 (24)
Does not follow a prospective/longitudinal design	9 (18)
*Report on the same cohort (e.g.* at an earlier follow-up stage)**	6 (12)
*Asthma status inadequately measured (e.g.* only uses stress biomarkers)**	5 (10)
Participants are not asymptomatic at baseline	7 (14)
Articles retained for systematic review	10 (20)
Total	49 (100)

Supplementary Material
Please note: supplementary material is not edited by the Editorial Office, and is uploaded as it has been supplied by the author.
supplementary tables ERR-0041-2014_Supplementary_material