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Long-term clinical and real-world experience with pirfenidone in the treatment of idiopathic pulmonary fibrosis

Vincent Cottin, Toby Maher
European Respiratory Review 2015 24: 58-64; DOI: 10.1183/09059180.00011514
Vincent Cottin
1National Reference Centre for Rare Pulmonary Diseases, Dept of Respiratory Medicine, Louis Pradel Hospital, Claude Bernard Lyon 1 University, UMR 754, Lyon, France
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Toby Maher
2National Heart and Lung Institute, Imperial College, London, UK
3NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK
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Article Information

vol. 24 no. 135 58-64
DOI 
https://doi.org/10.1183/09059180.00011514
PubMed 
25726556

Published By 
European Respiratory Society
Print ISSN 
0905-9180
Online ISSN 
1600-0617
History 
  • Received November 21, 2014
  • Accepted January 5, 2015
  • Published online February 28, 2015.

Copyright & Usage 
Copyright ©ERS 2015. ERR articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

Author Information

  1. Vincent Cottin1 and
  2. Toby Maher2,3
  1. 1National Reference Centre for Rare Pulmonary Diseases, Dept of Respiratory Medicine, Louis Pradel Hospital, Claude Bernard Lyon 1 University, UMR 754, Lyon, France
  2. 2National Heart and Lung Institute, Imperial College, London, UK
  3. 3NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK
  1. Vincent Cottin, Hôpital Louis Pradel, Service de Pneumologie, 28 Avenue Doyen Lepine, 69677 Lyon Cedex, France. E-mail: vincent.cottin{at}chu-lyon.fr
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Vol 24 Issue 135 Table of Contents
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Long-term clinical and real-world experience with pirfenidone in the treatment of idiopathic pulmonary fibrosis
Vincent Cottin, Toby Maher
European Respiratory Review Mar 2015, 24 (135) 58-64; DOI: 10.1183/09059180.00011514

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Long-term clinical and real-world experience with pirfenidone in the treatment of idiopathic pulmonary fibrosis
Vincent Cottin, Toby Maher
European Respiratory Review Mar 2015, 24 (135) 58-64; DOI: 10.1183/09059180.00011514
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  • Article
    • Abstract
    • Abstract
    • Introduction
    • Overview of the pirfenidone clinical development programme
    • Pirfenidone treatment-emergent adverse events in the CAPACITY and ASCEND trials
    • Pirfenidone safety and tolerability in long-term observational studies
    • Single-centre real-world experience with pirfenidone
    • Managing pirfenidone-related adverse effects in clinical practice
    • Treatment initiation in IPF
    • Treatment goals
    • Treatment adherence with pirfenidone
    • Timing of adverse events with pirfenidone
    • Prevention and management of gastrointestinal side-effects
    • Prevention and management of rash or photosensitivity
    • Conclusion
    • Acknowledgements
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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  • Interstitial and orphan lung disease
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