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vol. 24 no. 135 102-114
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History
- Received April 27, 2014
- Accepted June 15, 2014
- Published online February 28, 2015.
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Copyright ©ERS 2015. ERR articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
Author Information
- 1Unità Operativa di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Azienda Ospedaliera Universitaria Gaetano Martino, Università degli studi di Messina, Messina, Italy
- 2Unità Operativa di Pneumologia e Terapia Semi-Intensiva Respiratoria – Servizio di Fisiopatologia Respiratoria ed Emodinamica Polmonare-Ospedale San Giuseppe MultiMedica, Milan, Italy
- Gianluca Bagnato, Division of Rheumatology, Dept of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria no. 1, 98100 Messina, Italy. E-mail: gianbagnato{at}gmail.com
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Vol 24 Issue 135
Table of Contents
Cellular interactions in the pathogenesis of interstitial lung diseases
Jump To
- Article
- Abstract
- Abstract
- Introduction
- Myofibroblasts: the effector cells of fibrosis
- Fibroblasts: resident cells, apoptosis and the transition to myofibroblasts
- Fibrocytes: circulating precursors of fibroblasts, collagen-producing monocytes and recruitment to the site of injury
- AECs: pivotal cells in IPF and their role in epithelial–mesenchymal transition
- Endothelial cells: vascular damage, EMT and progenitors
- Pericytes and pleural mesothelial cells: underestimated contributors to mesenchymal transition
- Macrophages: monocyte recruitment, alternative activation and defective efferocytosis
- Lymphocytes: Th2-polarised response and antibody production
- Mast cells: fibrogenesis and lung infiltration
- Polymorphonuclear cells: inflammation and reactive oxygen species injury
- Conclusion
- Footnotes
- References
- Figures & Data
- Info & Metrics