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Looking to the future: a new decade of pulmonary arterial hypertension therapy

V.V. McLaughlin
European Respiratory Review 2011 20: 262-269; DOI: 10.1183/09059180.00006411
V.V. McLaughlin
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    Figure 1.

    Definition of a morbidity/mortality event: primary end-point used in the SERAPHIN trial. PAH: pulmonary arterial hypertension; 6MWD: 6-min walk distance; WHO FC: World Health Organization functional class; RHF: right heart failure; PDE-5i: phosphodiesterase-5 inhibitor; ERA: endothelin receptor antagonist.

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    Figure 2.

    Change in pulmonary vascular resistance (PVR) from baseline to week 17 in a randomised, placebo-controlled phase II trial of selexipag in patients with pulmonary arterial hypertension. Data are presented as geometric means with 95% confidence intervals. #: Wilcoxon rank sum test. Reproduced from [37] with permission from the publisher.

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Looking to the future: a new decade of pulmonary arterial hypertension therapy
V.V. McLaughlin
European Respiratory Review Dec 2011, 20 (122) 262-269; DOI: 10.1183/09059180.00006411

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Looking to the future: a new decade of pulmonary arterial hypertension therapy
V.V. McLaughlin
European Respiratory Review Dec 2011, 20 (122) 262-269; DOI: 10.1183/09059180.00006411
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  • Article
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    • NEW AGENTS TARGETING ESTABLISHED PATHWAYS IN PAH
    • AGENTS TARGETING NEW PATHWAYS IN PAH
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  • Pulmonary vascular disease
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