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Pulmonary alveolar proteinosis

R. Borie, C. Danel, M-P. Debray, C. Taille, M-C. Dombret, M. Aubier, R. Epaud, B. Crestani
European Respiratory Review 2011 20: 98-107; DOI: 10.1183/09059180.00001311
R. Borie
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C. Danel
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M-P. Debray
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C. Taille
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M-C. Dombret
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M. Aubier
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R. Epaud
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B. Crestani
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  • For correspondence: bruno.crestani@bch.aphp.fr
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    Figure 1.

    Chest radiograph of a patient with auto-immune pulmonary alveolar proteinosis showing diffuse alveolar opacities with a peri-hilar and basal distribution.

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    Figure 2.

    Chest computed tomography scan of a patient with auto-immune pulmonary alveolar proteinosis. Reticulations are superimposed on ground-glass opacities forming a “crazy paving” pattern with a geographic distribution: juxtaposition of healthy and sick zones. a) A horizontal section and b) a coronal section.

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    Figure 3.

    Bronchoalveolar lavage fluid with a milky appearance in a) normal saline compared to b) pulmonary alveolar proteinosis.

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    Figure 4.

    Periodic acid-Schiff (PAS) staining of bronchoalveolar lavage fluid with pulmonary alveolar proteinosis showing extracellular globular hyaline material homogeneously PAS positive with large, foamy macrophages containing eosinophilic granules. Magnification 400x.

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    Figure 5.

    Ultrastructural analysis of bronchoalveolar lavage fluid with pulmonary alveolar proteinosis showing numerous lamellar bodies.

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    Figure 6.

    Chest computed tomography (CT) scan of a patient with pulmonary alveolar proteinosis secondary to myelodysplastic syndrome. The CT scan shows ground-glass opacities and reticulations mainly in the lower zone with patchy, slightly peripheral distribution. a) A horizontal section and b) coronal section.

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Pulmonary alveolar proteinosis
R. Borie, C. Danel, M-P. Debray, C. Taille, M-C. Dombret, M. Aubier, R. Epaud, B. Crestani
European Respiratory Review Jun 2011, 20 (120) 98-107; DOI: 10.1183/09059180.00001311

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Pulmonary alveolar proteinosis
R. Borie, C. Danel, M-P. Debray, C. Taille, M-C. Dombret, M. Aubier, R. Epaud, B. Crestani
European Respiratory Review Jun 2011, 20 (120) 98-107; DOI: 10.1183/09059180.00001311
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