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Antifibrotic activities of pirfenidone in animal models

C.J. Schaefer, D.W. Ruhrmund, L. Pan, S.D. Seiwert, K. Kossen
European Respiratory Review 2011 20: 85-97; DOI: 10.1183/09059180.00001111
C.J. Schaefer
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D.W. Ruhrmund
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L. Pan
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S.D. Seiwert
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K. Kossen
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Article Information

vol. 20 no. 120 85-97
DOI 
https://doi.org/10.1183/09059180.00001111
PubMed 
21632796

Published By 
European Respiratory Society
Print ISSN 
0905-9180
Online ISSN 
1600-0617
History 
  • Received February 3, 2011
  • Accepted February 19, 2011
  • Published online June 1, 2011.

Copyright & Usage 
©ERS 2011

Author Information

  1. C.J. Schaefer,
  2. D.W. Ruhrmund,
  3. L. Pan,
  4. S.D. Seiwert and
  5. K. Kossen⇓
  1. InterMune Inc., Brisbane, CA, USA.
  1. K. Kossen, 3280 Bayshore Blvd, Brisbane, CA, 94005, USA. E-mail: kkossen{at}intermune.com
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Antifibrotic activities of pirfenidone in animal models
C.J. Schaefer, D.W. Ruhrmund, L. Pan, S.D. Seiwert, K. Kossen
European Respiratory Review Jun 2011, 20 (120) 85-97; DOI: 10.1183/09059180.00001111

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Antifibrotic activities of pirfenidone in animal models
C.J. Schaefer, D.W. Ruhrmund, L. Pan, S.D. Seiwert, K. Kossen
European Respiratory Review Jun 2011, 20 (120) 85-97; DOI: 10.1183/09059180.00001111
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  • Article
    • Abstract
    • SUMMARY OF CLINICAL TRIALS IN IPF
    • PHARMACOKINETICS IN HUMANS AND NONCLINICAL SPECIES
    • EFFECTS IN MODELS OF PULMONARY FIBROSIS
    • EFFECTS IN MODELS OF CARDIAC FIBROSIS
    • EFFECTS IN MODELS OF RENAL FIBROSIS
    • EFFECTS IN MODELS OF HEPATIC FIBROSIS
    • EFFECTS ON MEDIATORS OF FIBROSIS
    • EFFECTS IN CELL-BASED ASSAYS
    • CONCLUSIONS
    • Acknowledgments
    • Footnotes
    • REFERENCES
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