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Update on diffuse parenchymal lung disease

S. Harari, A. Caminati
European Respiratory Review 2010 19: 97-108; DOI: 10.1183/09059180.00002510
S. Harari
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A. Caminati
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Figures

  • FIGURE 1.
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    FIGURE 1.

    Definite usual interstitial pneumonia pattern. High-resolution computed tomography demonstrates honeycombing in a predominantly peripheral distribution.

  • FIGURE 2.
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    FIGURE 2.

    A pattern consistent with usual interstitial pneumonia pattern. High-resolution computed tomography image demonstrates irregular intralobular reticular opacity, ground-glass opacity and traction bronchiectasis in a predominantly peripheral distribution. There is no extensive honeycombing.

  • FIGURE 3.
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    FIGURE 3.

    Pattern high-resolution computed tomography consistent with nonspecific interstitial pneumonia in a patient with histological diagnosis of usual interstitial pneumonia. Ground-glass opacities, reticulation and marked traction bronchiectasis are present in the lung.

  • FIGURE 4.
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    FIGURE 4.

    High-resolution computed tomography with nonspecific interstitial pneumonia pattern in a patient with connective tissue disease; bilateral reticulation and ground-glass are present. Although the abnormality shows peripheral predominance in about one-third of cases, the relative sparing of the immediate sub-pleural zone of lung seen in ∼20% of cases may sometimes be a helpful diagnostic finding.

  • FIGURE 5.
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    FIGURE 5.

    Nonspecific interstitial pneumonia fibrosing pattern in a case of connective tissue disease. a) The alveolar walls are thickened by interstitial fibrosis and chronic inflammation. b) Hyperplasia of the lymphoid tissue is present.

  • FIGURE 6.
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    FIGURE 6.

    a) High-resolution computed tomography shows innumerable ill-defined centrilobular ground-glass opacity nodules, characteristic of sub-acute hypersensitivity pneumonitis. Note that there are also foci of relative sparing associated with air trapping. b) Evidence of fibrosis with irregular reticular opacities, traction bronchiectasis and architectural distortion in chronic hypersensitivity pneumonitis. A large cyst is present in the lower right lobe.

  • FIGURE 7.
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    FIGURE 7.

    High-resolution computed tomography (HRCT) showing typical changes in a patient with advanced definite lymphangioleiomyomatosis: extensive cystic changes are present. HRCT shows numerous discrete, round, thin-walled lung cysts.

  • FIGURE 8.
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    FIGURE 8.

    a) Significant emphysema in upper lobes and b) fibrosis in lower lobes in a patient with combined pulmonary fibrosis and emphysema.

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Update on diffuse parenchymal lung disease
S. Harari, A. Caminati
European Respiratory Review Jun 2010, 19 (116) 97-108; DOI: 10.1183/09059180.00002510

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Update on diffuse parenchymal lung disease
S. Harari, A. Caminati
European Respiratory Review Jun 2010, 19 (116) 97-108; DOI: 10.1183/09059180.00002510
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  • Article
    • IDIOPATHIC PULMONARY FIBROSIS
    • NONSPECIFIC INTERSTITIAL PNEUMONIA
    • CONNECTIVE TISSUE DISEASE
    • LYMPHANGIOLEIOMYOMATOSIS
    • PH IN DPLD
    • Statement of interest
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More in this TOC Section

  • The efficacy of bedside chest ultrasound
  • Pulmonary manifestations of Sjögren's syndrome
  • Cystic lung disease
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