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Retrosternal and pleural “bridging” fibrosis mimicking malignancy in a patient exposed to asbestos

M-P. Debray, S. Marchand-Adam, R. Soufan, J. Ostinelli, P-Y. Brillet, E. Schouman-Claeys, B. Crestani
European Respiratory Review 2010 19: 158-160; DOI: 10.1183/09059180.00000310
M-P. Debray
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S. Marchand-Adam
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R. Soufan
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J. Ostinelli
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P-Y. Brillet
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E. Schouman-Claeys
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B. Crestani
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  • FIGURE 1.
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    FIGURE 1.

    Contrast-enhanced computed tomography of the chest performed in 2002 showing a moderate right pleural effusion without clear pleural thickening or mediastinal mass.

  • FIGURE 2.
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    FIGURE 2.

    Contrast-enhanced computed tomography of the chest in the a) axial and b) sagittal planes. Computed tomography was performed in May 2007 when the patient complained of retrosternal pain. The images demonstrate an elongated retrosternal mass with regular borders merging with a thick right pleural thickening.

  • FIGURE 3.
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    FIGURE 3.

    Positron emission tomography scan in the axial plane performed in June 2007 showing intense and homogeneous increased uptake of 18-fluorodeoxyglucose within the mass (with a standard uptake value of 5). Note the physiological increased uptake of the myocardium.

  • FIGURE 4.
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    FIGURE 4.

    Photomicrograph of the mass removed from surgery showing numerous inflammatory cells interspersed with collagen bundles consistent with mediastinal fibrosis. Haematoxylin and eosin stain. Scale bar = 200 μm.

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Retrosternal and pleural “bridging” fibrosis mimicking malignancy in a patient exposed to asbestos
M-P. Debray, S. Marchand-Adam, R. Soufan, J. Ostinelli, P-Y. Brillet, E. Schouman-Claeys, B. Crestani
European Respiratory Review Jun 2010, 19 (116) 158-160; DOI: 10.1183/09059180.00000310

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Retrosternal and pleural “bridging” fibrosis mimicking malignancy in a patient exposed to asbestos
M-P. Debray, S. Marchand-Adam, R. Soufan, J. Ostinelli, P-Y. Brillet, E. Schouman-Claeys, B. Crestani
European Respiratory Review Jun 2010, 19 (116) 158-160; DOI: 10.1183/09059180.00000310
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