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Epidemiology of COPD

C. Raherison, P-O Girodet
European Respiratory Review 2009 18: 213-221; DOI: 10.1183/09059180.00003609
C. Raherison
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P-O Girodet
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  • FIGURE 1.
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    FIGURE 1.

    Decrease in forced expiratory volume in 1 s (FEV1) according to smoking status. Adapted from [37].

  • FIGURE 2.
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    FIGURE 2.

    Prevalence of chronic bronchitis in relation to active smoking, stratified by age. □: nonsmokers; ▒: 1–10 cigarettes per day; ░: 11–20 cigarettes per day; ▪: >20 cigarettes per day. Reproduced from [15] with permission from the publisher.

  • FIGURE 3.
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    FIGURE 3.

    Impact of risk factors in the occurrence of chronic obstructive pulmonary disease. FEV1: forced expiratory volume in 1 s; % pred: % predicted. Proposal for a theoretical model adapted from Rijcken and Britton [15].

Tables

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  • Table. 1—

    Estimate of prevalence according to diagnostic criteria

    CriteriaSurveys nPooled prevalence % (95% CI)
    COPD377.6 (6–9.5)
     Spirometry269.2 (7.7–11)
     Reported by patient74.9 (2.8–8.3)
     Diagnosed by a doctor45.2 (3.3–7.9)
     Clinical/radiological examination113.7 (12.9–14.5)
    Chronic bronchitis386.4 (5.3–7.7)
     Productive moist cough296.7 (5.4–8.2)
     Reported by patient155.3 (3.9–7.1)
    Emphysema81.8 (1.3–2.6)
     Clinical/radiological examination13.2 (2.8–3.6)
     Reported by patient71.7 (1.2–2.5)
    • COPD: chronic obstructive pulmonary disease. Modified and reproduced from [14] with permission from the publisher.

  • Table. 2—

    Prevalence of chronic obstructive pulmonary disease according to demographic criteria

    Studies nCumulative prevalence % (95% CI)p-value
    All377.6 (6–9.5)
    Age<0.0001
     <40 yrs93.1 (1.8–5)
     ≥40 yrs349.9 (8.2–11.8)
     40–64 yrs238.2 (6.5–10.3)
     ≥65 yrs1114.2 (11–18)
    Status<0.0001
     Active smoker1715.4 (11.2–20.7)
     Ex-smoker1610.7 (8.1–14)
     Nonsmoker164.3 (3.2–5.7)
    Sex0.0002
     Male279.8 (8–12.1)
     Female275.6 (4.4–7)
    Geographic zone0.77
     Africa0
     America34.6 (2.8–7.6)
     Europe287.4 (5.9–9.3)
     South-east Asia211.4 (4.4–26.4)
     Pacific49 (3–24.1)
    Sample0.04
     Urban1210.2 (7.4–13.9)
     Rural48 (3.9–15.8)
     Mixed216.1 (4.9–7.7)
    • Modified and reproduced from [14] with permission from the publisher.

  • Table. 3—

    Principal comorbidities associated with chronic obstructive pulmonary disease

    Cardiovascular
     Coronary artery disease High blood pressure Left heart failure Tachyarrhythmia
    Malignant tumours
     Nonsmall cell lung cancer
    Respiratory
     Pneumonia Pulmonary embolism Chronic cor pulmonale Asthma Rhinitis
    Endocrine
     Obesity Diabetes Dyslipidaemia Denutrition
    Gastroenterology
     Gastric ulcer Gastro-oesophageal reflux
    Osteoarticular
     Fractures Osteoporosis
    Psychiatric
     Depression Anxiety
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Epidemiology of COPD
C. Raherison, P-O Girodet
European Respiratory Review Dec 2009, 18 (114) 213-221; DOI: 10.1183/09059180.00003609

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Epidemiology of COPD
C. Raherison, P-O Girodet
European Respiratory Review Dec 2009, 18 (114) 213-221; DOI: 10.1183/09059180.00003609
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  • Article
    • Abstract
    • ESTIMATE OF PREVALENCE OF COPD
    • SCREENING FOR COPD
    • IMPACT OF COPD ON MORBIDITY
    • MORTALITY ATTRIBUTABLE TO COPD
    • RISK FACTORS FOR COPD
    • Statement of interest
    • Provenance
    • References
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