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The promoter polymorphism -1562C/T in matrix metalloproteinase-9 and COPD severity

D. G. Yanbaeva, G. F. Korytina, L. Z. Akhmadishina, S. Z. Zagidullin, T. V. Victorova
European Respiratory Review 2006 15: 230-232; DOI: 10.1183/09059180.00010131
D. G. Yanbaeva
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G. F. Korytina
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L. Z. Akhmadishina
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S. Z. Zagidullin
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T. V. Victorova
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    FIGURE 1.

    Matrix metalloproteinase 9 genotypes and chronic obstructive pulmonary disease (COPD) severity. ░: genotype CC; ▒: genotype CT+genotype TT.

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    Basic characteristic of study groups

    CharacteristicsCOPDControls
    Total309305
    Male243 (79%)222 (73%)
    Female61 (21%)84 (27%)
    Age (mean±sem) yrs61.5±12.756.1±8.6
    FEV1 % pred39.8±6.2ND
    Smokers168 (55%)152 (50%)
    Nonsmokers138 (45%)153 (50%)
    Smoking index pack-yrs35.9±5.327.6±3.7
    • COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; ND: not determined.

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The promoter polymorphism -1562C/T in matrix metalloproteinase-9 and COPD severity
D. G. Yanbaeva, G. F. Korytina, L. Z. Akhmadishina, S. Z. Zagidullin, T. V. Victorova
European Respiratory Review Dec 2006, 15 (101) 230-232; DOI: 10.1183/09059180.00010131

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The promoter polymorphism -1562C/T in matrix metalloproteinase-9 and COPD severity
D. G. Yanbaeva, G. F. Korytina, L. Z. Akhmadishina, S. Z. Zagidullin, T. V. Victorova
European Respiratory Review Dec 2006, 15 (101) 230-232; DOI: 10.1183/09059180.00010131
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